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Found 243 clinical trials
Tranexamic Acid in Proximal Humeral Fractures

The purpose of this study is to determine the effect of tranexamic acid (on blood loss and transfusion requirements in patients with proximal humeral fractures requiring open surgical approaches. This a blinded, controlled, therapeutic trial in which the patients will be randomized to receive TXA or no drug intervention. The …

humeral fracture
  • 0 views
  • 04 Oct, 2022
  • 1 location
Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion

The purpose of this study is to compare the experiences of subjects who drain malignant (cancerous) pleural effusions (fluid) from around their lung(s) in a more frequent manner using a talc instilled via tunneled pleural catheter combined with daily drainage and those subjects who drain this fluid in a daily …

malignant pleural effusion
drainage
pleural fluid analysis
dyspnea
thoracentesis
  • 0 views
  • 28 Jul, 2021
  • 1 location
Efficacy of Pericapsular Nerve Group Block

Hip fracture is a common orthpaedic problem especially in elderly population. Fascia iliaca compartment block (FICB) and femoral nerve block are well-established technique as part of peri-operative multimodal analgesia for hip fractures. Reviews have shown peripheral nerve blocks including FICB, femoral nerve block and 3-in-1 block could reduce both pain …

analgesia
nerve block
opioid
pain relieving
  • 0 views
  • 19 Dec, 2021
  • 1 location
Early Intervention After Rape to Prevent Post-traumatic Stress Disorder - a Multicenter Randomized Control Trial (EIR)

Rape is a common cause of post-traumatic stress disorder (PTSD) among women, as around 30-50% will develop PTSD in the aftermath of rape. A modified protocol based on Prolonged Exposure Therapy (mPE), has been developed, consisting of three to five once or twice weekly 60 minutes sessions, and studies indicate …

  • 0 views
  • 24 Oct, 2022
N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension.

This study will evaluate the use of N-acetyl cysteine in post-reperfusion pulmonary injury in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary balloon angioplasty and pulmonary endarterectomy. Half of the patients will receive N-acetyl cysteine and the other placebo.

endarterectomy
balloon angioplasty
  • 0 views
  • 26 Jan, 2021
  • 1 location
Endovenous Laser Ablation in Acute Thrombophlebitis of the Varicose Great Saphenous Vein

rospective single-centre randomized open-label study for comparison three modes of treatment for thrombosis of varicose great saphena vein - standard medical with fondaparinux sodium for 45 days, endovenous laser ablation close to the saphenofemoral junction with a 7-day course of anticoagulation and endovenous laser ablation close to the saphenofemoral junction …

  • 0 views
  • 27 Aug, 2021
  • 1 location
BTE and Pulsed Waveforms for Cardioversion of Atrial Fibrillation - Escalation Strategy and Manual Pressure

Background: A Danish study raised the question of the usefulness of escalating energy protocols compared to fixed high-energy protocols. Maximal energies are usually the final choice of the physicians. Some authors showed that decreasing impedance by manual pressure application (MPA) had a positive impact on cardioversion outcome. This is likely …

fibrillation
cardioversion
shock
  • 0 views
  • 04 Oct, 2022
  • 1 location
Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study

The purpose of this study is to evaluate the efficacy and safety of rivaroxaban for the prevention of deep vein thrombosis in patients with left iliac vein compression treated with stent implantation.

  • 0 views
  • 28 Jan, 2021
  • 9 locations
Leiden Trial In Prevention of Post-Operative ThromboEmbolic Events (TIPOTEE)

In neurosurgical patients, the risk for venous thromboembolic events (VTE) is high due to the relatively long duration of surgery, the high occurrence of prolonged immobilization of patients due to paresis of the legs or intracranial pathology causing inability to mobilise2. Moreover, intracranial and intraspinal tumours and subarachnoid haemorrhage cause …

cancer
clot
venous thrombosis
thromboembolism
thrombophilia
  • 7 views
  • 24 Apr, 2022
  • 1 location
Preventing de Novo Portal Vein Thrombosis With Antithrombin-III in Patients With Cirrhosis

To prevent portal vein thrombosis (PVT) in patients with cirrhosis at risk for PVT by pharmacologic prophylaxis with intravenous antithrombin (AT-III).

liver disease
portal vein thrombosis
biopsy of liver
hepatitis
  • 0 views
  • 02 Jul, 2021
  • 1 location