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Found 4467 clinical trials
Cerebral Oxygenation and Burst Suppression

investigators want to observe a group of pediatric patients who are going to undergo open thoracic surgery at Queen Silvia's child and youth hospital, Sahlgrenska University Hospital. Population that has been selected is between 6-36 months due to the fact that the physiological development does not differ significantly with respect …

  • 04 Oct, 2022
  • 1 location
Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver Disease (EvaLongCovid)

The project is essential to understand the impact of the COVID-19 pandemic in patients with Chronic Liver Disease (CLD). The impact has been felt due to direct risk of COVID infection in self, or in caregivers, lack of access to services during lockdown, interruptions in transplant listing and waitlist mortality. …

liver transplant
liver disease
  • 15 Jun, 2022
  • 1 location
Investigation of Prognostic Biomarkers, Host Factors and Viral Factors for COVID-19 Associated Encephalopathy/Encephalitis and Multi-systemic Inflammatory Syndrome in Children

Background and objective From this April, there was a COVID-19 outbreak in Taiwan. The first fatal case of pediatric COVID-19 encephalitis was reported on April 19, 2022 and fatal fulminant cerebral edema in other 4 children with COVID-19 encephalitis was reported within 1 month from Taiwan CDC registry. To date, …

Accepts healthy volunteers
  • 28 Oct, 2022
  • 1 location
Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin, including patients with osteomyelitis, complicated urinary tract infection, nosocomial lower respiratory tract infection, bacterial meningitis/central nervous system infection, bacteraemia/sepsis, skin and …

infection, nosocomial
bacterial infection
  • 27 Jan, 2022
  • 24 locations
The circTeloDIAG: Liquid Biopsy for Glioma Tumor

Gliomas represent the most frequent primary brain tumor, with 2,500 to 3,000 new cases per year in France. Their diagnosis, although highly complex, is essential for determining patient management. While grade I gliomas (infrequent) are curable by surgery or present a slow progression, grades II to IV require heavy treatment …

primary brain tumors
brain tumor
recurrent glioma
  • 17 Aug, 2021
  • 1 location
Preoperative Radiotherapy and Systemic Therapy Following Surgery in 'de Novo' Metastatic Breast Cancer

Locoregional (LRT) of the primary tumor in de-novo metastatic breast cancer (dnMBC) is no longer only a surgical challenge, but more the final decision of a multidisciplinary tumor board including medical oncologists, radiation oncologists and surgical oncologists. It is no longer only a question of locoregional control but rather a …

  • 17 May, 2022
  • 1 location
Nutrition and Inflammation in Patients With Head and Neck Cancer

An estimated 1500 people in Sweden will annually be diagnosed with head and neck cancer (HNC). Five year survival is approximately 69%. Long-term sequelae are common and in particular nutritional problems and fatigue. Radiotherapy (RT) is the cornerstone of treatment, either as single modality treatment or combined modality treatment. RT …

head and neck cancer
neck cancer
nutritional problems
  • 29 Oct, 2021
  • 1 location
Intestinal Flora Research Plan for Critically Ill Patients

More and more critically ill patients have improved early survival, they have been suffering from organ damage and inflammation for a long time, which is called chronic critical illness (CCI). Among CCI, persistent inflammatory response-immunosuppression-catabolic syndrome (PICS) is a special type of chronic severe disease, and immune paralysis is its …

  • 24 Jan, 2021
  • 1 location
Early Detection of Familial Hypercholesterolemia in Children (DECOPIN)

Heterozigous FH is an underdiagnosed disease in the paediatric population. Its early detection, would allow us to initiate lifestyle therapeutical changes and early pharmacological therapy if necessary. This is a key fact to reduce atherosclerosis progression and cardiovascular risk in adulthood. Moreover, it will allow, detecting the first and second …

genetic disorder
early diagnosis
  • 04 Mar, 2022
  • 2 locations
Magnetic Resonance Technics for the Assessment of Liver Function Before and After TIPS

Portal hypertension is the end-stage fatal complications of liver cirrhosis. Decompensated cirrhosis patients can pass through transjugular intrahepatic portosystemic shunt to effectively prevent bleeding and refractory ascites. However, the occurrence of hepatic encephalopathy and liver function failure, infection, bleeding again are main lethality postoperative complications after TIPS. The accurate TIPS …

portosystemic shunt
venous pressure
  • 05 Feb, 2022
  • 1 location