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Found 4599 clinical trials
Featured trial
COPD Exacerbation Research Study

Looking for patients at least 40 years of age who have been diagnosed with COPD and recently had several events of worsening of symptoms.  

  • 125 views
  • 23 Nov, 2020
  • 1 location
Featured trial
NO 0050-0637

ICON Early Phase Services is conducting a non-interventional device research study adults age 40+ who are either healthy, or, have chronic obstructive pulmonary disease (COPD). This study is being

  • 613 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Phase III Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ensifentrine over 24 Weeks in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease.

identical over the first 24 weeks. The 48-week subset will continue to assess long-term safety in this subset of patients.  Both studies will assess lung function, symptoms, and quality of life

  • 164 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Add on treatment for COPD for patients who experience frequent exacerbations

Current or former smokers who are diagnosed with COPD and experienced at least 2 exacerbations- worsening of symptoms requiring steroid treatment or hospitalization despite being on multiple inhaler medications may qualify for this study involving benralizumab subcutaneous injections compared to placebo injections, initially every 4 weeks, then every 8 weeks …

  • 0 views
  • 09 Jun, 2022
  • 1 location
Featured trial
Albuterol in Patients With Lymphangioleiomyomatosis

Background: Lymphangioleiomyomatosis (LAM) is a rare type of lung disease that occurs almost exclusively in women. In LAM, muscle tissue grows in the lungs and starts

lymphangioleiomyomatosis
  • 94 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Eosinophilic Asthma Research Study

Qualified participants will not be charged to receive:• Study medicine and study-related office visits • Study-related ECG, lung function tests, and lab work • You may be compensated for time

  • 3 views
  • 21 Dec, 2021
  • 1 location
Featured trial
Asthma Sample Collection Protocol

Fiberoptic bronchoscopy is a procedure which involves passing a pencil-thin tube into the lung in order to collect fluid and cells from the airways. Fiberoptic bronchoscopy can collect cells from

  • 315 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …

non-squamous non-small cell lung cancer
advanced non-squamous non-small cell lung cancer
cancer
lung cancer
platinum-based chemotherapy
  • 535 views
  • 04 May, 2022
  • 143 locations
Featured trial
Phase 3 Study of MRTX849 vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-12)

This Phase 3 study will evaluate the efficacy of the investigational agent MRTX849 versus docetaxel in patients who have been previously treated for metastatic NSCLC with a KRAS G12C mutation.

advanced lung cancer
refractory non-small cell lung cancer
recurrent non-small cell lung cancer
metastatic non-small cell lung cancer
lung cancer
  • 34 views
  • 22 Jun, 2022
  • 154 locations
Featured trial
Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

KRAS
pembrolizumab
  • 36 views
  • 22 Jun, 2022
  • 64 locations