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Found 157 clinical trials
Study of Efficacy and Safety of LTP001 in Pulmonary Arterial Hypertension

The purpose of this study is to explore the efficacy and safety of LTP001 in participants with pulmonary arterial hypertension (PAH) to determine if LTP001 has an adequate clinical profile to

  • 0 views
  • 24 Jul, 2022
  • 2 locations
A Phase 3 Study to Evaluate the Safety and Tolerability of L606 in Subjects With PAH

This single-arm, Phase 3, 2-part, open-label, multicenter study aims to demonstrate the safety and tolerability of L606 in patients with PAH switching from a stable Tyvaso dose. The study will

  • 1 views
  • 21 Mar, 2022
  • 1 location
Microbiota Transplant Therapy for Pulmonary Arterial Hypertension: Early Safety and Feasibility Study

This pilot clinical trial will evaluate the initial safety and feasibility of intestinal microbiota transplantation (IMT) in patients with pulmonary arterial hypertension (PAH). This trial will

  • 4 views
  • 08 Dec, 2021
  • 1 location
Safety, Tolerability, & Pharmacokinetics Study of Single & Multiple Inhaled Doses of Imatinib Inhalation Solution

This is a randomised, double-blind, placebo-controlled, dose escalation study to evaluate the safety, tolerability, and PK of single and multiple inhaled doses of imatinib inhalation solution (AER-901) in healthy adult volunteers. This study consists of 2 parts and an optional third part: Part A: double-blind, placebo-controlled, single ascending dose (SAD). …

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Pulmonary Arterial Hypertension or PAH is a progressive condition for which there is no cure. Even with substantial pharmacologic advances in the modern treatment era, survival still remains

  • 100 views
  • 25 Mar, 2021
  • 1 location
Effects of DHEA in Pulmonary Hypertension (EDIPHY)

imaging at 18 weeks compared to placebo and to assess side effects and safety in pulmonary arterial hypertension.

hypertension
ventilation perfusion lung scan
forced expiratory volume
pulmonary function test
pulmonary disease
  • 17 views
  • 27 Apr, 2022
  • 1 location
Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension

arterial hypertension.

hypertension
diuretics
digoxin
ambrisentan
  • 0 views
  • 24 Jan, 2021
  • 1 location
COMPression of Left Main coRonary artEry in patientS With Pulmonary Arterial Hypertension aSymptomatIc fOr aNgina (COMPRESSION)

The prevalence of critical ab extrinsic compression of left main coronary artery (LMCA) is very high in patients with pulmonary arterial hypertension (PAH) symptomatic for angina (up to 40

  • 0 views
  • 16 Jun, 2022
  • 1 location
A Study of Single and Multiple Doses of Different Formulations of a Prostacyclin Receptor Agonist

The purpose of the study is to assess safety and tolerability of prostacyclin receptor agonist formulation in treatment period 1 and with different formulation of prostacyclin receptor agonist in treatment period 2.

Accepts healthy volunteers
  • 0 views
  • 24 Jul, 2022
  • 1 location
A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension

The purpose of this study is to evaluate the effect of macitentan on hemodynamic measures at Week 24 in pediatric populations.

  • 0 views
  • 22 Jul, 2022
  • 8 locations