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Found 212 clinical trials
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Open Label Study of Treprostinil Palmitil Inhalation Powder (TPIP) In Pulmonary Arterial Hypertension (PAH)

The main purpose of this study is to evaluate the safety and tolerability of single doses of treprostinil palmitil inhalation powder (TPIP) in participants with pulmonary arterial hypertension

  • 0 views
  • 25 Nov, 2021
  • 2 locations
None
Olaparib for PAH: a Multicenter Clinical Trial

, pulmonary arterial hypertension (PAH), to early-phase clinical trials. We, and others, have published strong evidence that DNA damage accounts for disease progression in PAH and showed that PARP1 inhibition

serum pregnancy test
body mass index
pulmonary disease
hysterectomy
cancer
  • 6 views
  • 05 Sep, 2021
  • 4 locations
None
Positioning Imatinib for Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension (PAH) is a rare condition in which a narrowing of blood vessels carrying blood through the lungs puts an increased work load on the heart; it has to work harder

  • 0 views
  • 27 Sep, 2021
  • 8 locations
None
A Study of GMA301 in Subjects With Pulmonary Arterial Hypertension

A Randomized, Placebo-Controlled, Double-blind, Dose Escalation Study to Assess Safety, Efficacy and Pharmacokinetics of GMA301 Injection in Subjects with Pulmonary Arterial Hypertension

right heart catheterization
heart disease
endothelin
pulmonary arterial pressure
hypertension
  • 0 views
  • 25 Jan, 2021
  • 8 locations
None
TranspulmonarY Estrogen Gradient and Estrogen Receptors (TYEGER) in PAH

Pulmonary arterial hypertension (PAH) is a disease characterized by elevated pressures in the blood vessels of the lungs that is not caused by another disease processes. More specifically, it is

left ventricular end-diastolic pressure
right heart catheterization
vascular disease
hpah
pulmonary arterial pressure
  • 0 views
  • 30 Jan, 2021
  • 1 location
None
Cardiac Function and Exercise Capacity in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension is characterized by a progressive increase in pulmonary vascular resistance inducing shortness of breath and exercise intolerance. We aim to correlate cardiac

hypertension
  • 7 views
  • 27 Jan, 2021
  • 15 locations
None
EXPEDITE: A Study of Remodulin Induction Followed by Orenitram Optimization to Treat Pulmonary Arterial Hypertension

) Injection in subjects with pulmonary arterial hypertension (PAH).

appetite suppressants
immunodeficiency
treprostinil
remodulin
heart disease
  • 97 views
  • 06 Aug, 2021
  • 10 locations
None
Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension

arterial hypertension.

ambrisentan
digoxin
diuretics
hypertension
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Effects of RT234 on Exercise Parameters Accessed by CPET in Subjects With PAH

pulmonary arterial hypertension (PAH).

scleroderma
overlap syndrome
immunodeficiency
right heart catheterization
calcium channel blockers
  • 0 views
  • 03 Jul, 2021
  • 5 locations
None
Acute Haemodynamic Study of TPN171H in Patients With Pulmonary Arterial Hypertension

This study is a phase IIa proof-of-concept study to evaluate the effect of single-dose TPN171H tablets on acute haemodynamic parameters in patients with pulmonary arterial hypertension.The trial is expected to include 60 patients, divided into 6 groups, according to 1:1:1:1:1:1 into the placebo group and the test drugs 2.5mg, 5mg, …

heart disease
tadalafil
connective tissue disease
hypertension
  • 0 views
  • 06 Nov, 2021
  • 9 locations