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Found 8 clinical trials
Hydroxychloroquin (HCQ) in chILD of Genetic Defect

The purpose of this proposed research is to investigate the efficacy and safety of hydroxychloroquine sulfate (HCQ, Quensyl) for pediatric ILD(chILD) caused by pulmonary surfactant-associated

  • 0 views
  • 27 Feb, 2022
  • 1 location
NCPAP+MISA vs. NIPPV+MISA to NRDS a Multicenter Randomized Study

NICU ward, infants were randomly assigned to NCPAP group and NIPPV group.Patients diagnosed with NRDS on non-invasive respiratory support (NIPPV or NCPAP) were given a therapeutic dose of pulmonary

  • 0 views
  • 05 Dec, 2021
  • 1 location
Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome(RDS)

In preterm infants with neonatal respiratory distress syndrome (RDS), exogenous pulmonary surfactant(PS) replacement therapy is one of the most important therapeutic breakthrough to reduce

  • 0 views
  • 21 Oct, 2022
  • 1 location
Effect of Autologous Cord Blood Mononuclear Cell in Preventing Complications of Monozygotic Twins in Very Premature Infants

weeks of postmenstrual age or discharge home. The secondary outcomes will include respiratory support duration, frequence of incubate, use of glucocorticoid, pulmonary surfactant and blood, duration of

Accepts healthy volunteers
  • 0 views
  • 29 Oct, 2021
  • 2 locations
Daping Hospital of the Third Military Medical University

In the clinical data, the changes of RIPK3 and FXR were monitored in the lung lavage fluid and blood from the patients. In vivo experiments to find high risk factors to induce AEC necrosis and further lead to ARDS evidence, can provide a more direct theoretical research foundation for the …

  • 0 views
  • 25 Oct, 2022
Late Surfactant After a Recruitment Maneuver in Extremely Low Gestational Age Newborns - LATE-REC-SURF Trial

This is an unblinded monocentric pilot superiority trial that will be conducted in a IIIlevel NICU at Fondazione Policlinico Agostino Gemelli - IRCCS. The aim of the study is to test the hypothesis that endotracheal administration of poractant alfa preceded by a recruitment manoeuvre in High-Frequency Oscillatory Ventilation (HFOV) modality …

  • 0 views
  • 14 Dec, 2021
  • 1 location
Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS)

In preterm infants with neonatal respiratory distress syndrome (NRDS), exogenous pulmonary surfactant(PS) replacement therapy is one of the most important therapeutic breakthrough to reduce

  • 0 views
  • 22 Oct, 2022
  • 1 location
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

In light of the rapidly emerging pandemic of SARS-CoV-2 infections, the global population and health care systems are facing unprecedented challenges through the combination of transmission and the potential for severe disease. Acute respiratory distress syndrome (ARDS) has been found with unusual clinical features dominated by substantial alveolar fluid load. …

respiratory infection
inflammatory response
acute respiratory distress
critical illness
cytokines
  • 0 views
  • 24 Jan, 2021