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Found 11 clinical trials
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Amnioinfusion Initiative

The aim of this study is to compare perinatal survival in patients presenting with early spontaneous PPROM and persistent oligohydramnios, managed either conservatively or with serial amnioinfusions.

  • 0 views
  • 07 Nov, 2020
  • 1 location
None
Physiological-based Cord Clamping in Congenital Diaphragmatic Hernia

with an isolated CDH. Before birth, infants will be randomised to either PBCC or immediate cord clamping, stratified by treatment centre and severity of pulmonary hypoplasia on antenatal ultrasound

diaphragmatic hernia
hypertension
congenital diaphragmatic hernia
pulmonary hypoplasia
umbilical cord clamping
  • 0 views
  • 12 Aug, 2021
  • 5 locations
None
Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia

mortality is estimated to be as high as 90% because of severe pulmonary hypoplasia due to the lack of amniotic fluid. Survivors have significant risk of renal impairment (90%) requiring dialysis or renal

  • 0 views
  • 30 Apr, 2021
  • 1 location
None
Fetoscopic Endoluminal Tracheal Occlusion (FETO) With Smart-TO

diaphragmatic hernia and moderate to severe pulmonary hypoplasia

  • 0 views
  • 08 Sep, 2021
  • 2 locations
None
Smart Removal for Congenital Diaphragmatic Hernia

with congenital diaphragmatic hernia and moderate to severe pulmonary hypoplasia.

  • 0 views
  • 07 Nov, 2021
  • 1 location
None
Feto-Endoscopic Tracheal Occlusion (FETO) for Left Congenital Diaphragmatic Hernia

Tracheal occlusion IDE approved by FDA for congenital diaphragmatic hernia fetuses.

pulmonary hypoplasia
Accepts healthy volunteers
diaphragmatic hernia
congenital diaphragmatic hernia
  • 3 views
  • 12 Nov, 2021
  • 1 location
None
Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia

CDH is a birth defect characterized by the development, very early in gestation, of a hole in the diaphragm, the breathing muscle that separates the chest from the abdomen. As a result, the intestines and other organs in the abdomen can move into the chest and press on the developing …

pulmonary hypoplasia
diaphragmatic hernia
  • 4 views
  • 28 Jan, 2021
  • 1 location
None
Milrinone in Congenital Diaphragmatic Hernia

Infants with congenital diaphragmatic hernia (CDH) usually have pulmonary hypoplasia and persistent pulmonary hypertension of the newborn (PPHN) leading to hypoxemic respiratory failure (HRF

mechanical ventilation
diaphragmatic hernia
right ventricular overload
vasodilator
pulmonary hypoplasia
  • 73 views
  • 03 Nov, 2021
  • 16 locations
None
Renal Anhydramnios Fetal Therapy

Early pregnancy renal anhydramnios or EPRA is a condition where a pregnant woman does not have any amniotic fluid around her fetus because of a problem with the fetus's kidneys. This condition is thought to be fatal once the fetus is born because of inadequate lung growth. The Renal Anhydramnios …

early pregnancy
prenatal
  • 214 views
  • 22 Oct, 2021
  • 11 locations
None
Fetoscopic Endoluminal Tracheal Occlusion

The purpose of this research study is to see if the FETO surgery and FETO release (surgery to remove the device) works and is safe for babies with severe right or left Congenital Diaphragmatic Hernia (CDH). CDH is a condition in which a hole in the baby's diaphragm allows the …

pulmonary hypoplasia
diaphragmatic hernia
  • 0 views
  • 02 Jul, 2021
  • 1 location