Found 210 clinical trials
Study to evaluate HZN-825 in patients with Idiopathic Pulmonary Fibrosis (IPF)
The goal is to determine the efficacy, safety and tolerability for 360 patients with Idiopathic Pulmonary Fibrosis (IPF) assigned to either one of 2 dose regimens of HZN-825 (administered once
- 10 views
- 22 Sep, 2022
- 28 locations
Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that becomes worse over time. There is currently no effective treatment for it. Researchers
- 178 views
- 23 Nov, 2020
- 1 location
A 24-week, double-blind, randomized, parallel-group study evaluating the efficacy and safety of oral nintedanib coadministered with oral sildenafil, compared to treatment with nintedanib alone, in patients with idiopathic pulmonary fibrosis (IPF) and advanced lung function impairment
patients with idiopathic pulmonary fibrosis (IPF) and advanced lung function impairment
- 1324 views
- 23 Nov, 2020
- 1 location
Low-Dose Danazol for the Treatment of Telomere Related Diseases
DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes can develop diseases of the bone marrow, lung, and liver. Researchers want to see …
- 348 views
- 22 Dec, 2020
- 1 location
Role of Genetic Factors in the Pathogenesis of Lung Disease
This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes …
- 358 views
- 23 Nov, 2020
- 1 location
HElping Alleviate the Longer-term Consequences of COVID-19 (HEAL-COVID)
HEAL-COVID is jointly Sponsored by Cambridge University Hospitals NHS Foundation Trust and The University of Cambridge. The acute effects of COVID-19 are now well described. Evidence is emerging of serious longer-term complications occurring in the convalescent phase of the illness in a significant proportion of patients particularly cardiovascular and pulmonary …
- 0 views
- 02 Aug, 2021
- 1 location
Telerehabilitation in Patients With Idiopathic Pulmonary Fibrosis
It is to determine the effectiveness of different telerehabilitation exercise programs received to 2 groups randomly formed in idiopathic pulmonary fibrosis (IPF) patients. The cases meeting the
- 0 views
- 23 Mar, 2022
- 1 location
PFOX: Pulmonary Fibrosis Ambulatory Oxygen Trial (PFOX)
The fibrotic interstitial lung diseases (fILD) are characterised by lung scarring, distressing breathlessness and poor health-related quality of life. Exertional desaturation (low blood oxygen during exercise) is a hallmark of fILD, occurring in over 50% of patients. It is sometimes treated with ambulatory oxygen therapy (AOT), which involves breathing supplemental …
- 3 views
- 12 Feb, 2022
- 1 location
Prednisone in Cystic Fibrosis Pulmonary Exacerbations (PIPE)
This will be a 5 year randomized, double blind, placebo controlled trial of 7 days of oral prednisone in cystic fibrosis (CF) patients receiving intravenous (IV) antibiotic treatment for a pulmonary exacerbation at the Hospital for Sick Children and other study sub-sites across Canada. The intervention will be oral prednisone …
- 38 views
- 03 Mar, 2022
- 12 locations