pulmonary fibrosis Clinical Research Trials

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Found 221 clinical trials

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Idiopathic Pulmonary Fibrosis

2074 views
08 Nov, 2020
1 location

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Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that becomes worse over time. There is currently no effective treatment for it. Researchers

ct scan

idiopathic pulmonary fibrosis

chest x-ray

x-rays

walk tests

162 views
23 Nov, 2020
1 location

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A 24-week, double-blind, randomized, parallel-group study evaluating the efficacy and safety of oral nintedanib coadministered with oral sildenafil, compared to treatment with nintedanib alone, in patients with idiopathic pulmonary fibrosis (IPF) and advanced lung function impairment

patients with idiopathic pulmonary fibrosis (IPF) and advanced lung function impairment

1316 views
23 Nov, 2020
1 location

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Low-Dose Danazol for the Treatment of Telomere Related Diseases

DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes can develop diseases of the bone marrow, lung, and liver. Researchers want to see …

hepatic fibrosis

lung disease

anemia

pulmonary fibrosis

liver disease

293 views
22 Dec, 2020
1 location

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Role of Genetic Factors in the Pathogenesis of Lung Disease

This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes …

diabetes

pulmonary fibrosis

pulmonary disease

bronchoscopy

120 views
23 Nov, 2020
1 location

Examination of Radiographic Progression Efficacy and Safety of Long-Term Treatment With Infliximab in Patients With Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a chronic inflammatory disease that involves the sacroiliac joints, axial skeleton, entheses and peripheral joints. Current therapy for AS is mainly NSAIDs and physiotherapy which are oft insufficient. Treatment with the TNF-alpha blocking agent infliximab was shown to have definite clinical efficacy in patients with active …

steroidal anti-inflammatory drugs

infliximab

tumor necrosis factor alpha

NSAID

anti-tumor necrosis factor therapy

51 views
07 Nov, 2020
8 locations

Prednisone in Cystic Fibrosis Pulmonary Exacerbations

This will be a 5 year randomized, double blind, placebo controlled trial of 7 days of oral prednisone in cystic fibrosis (CF) patients receiving intravenous (IV) antibiotic treatment for a pulmonary exacerbation at the Hospital for Sick Children and other study sub-sites across Canada. The intervention will be oral prednisone …

32 views
26 Jan, 2021
1 location

PFOX: Pulmonary Fibrosis Ambulatory Oxygen Trial

The fibrotic interstitial lung diseases (fILD) are characterised by lung scarring, distressing breathlessness and poor health-related quality of life. Exertional desaturation (low blood oxygen during exercise) is a hallmark of fILD, occurring in over 50% of patients. It is sometimes treated with ambulatory oxygen therapy (AOT), which involves breathing supplemental …

3 views
08 Mar, 2021
2 locations

Management of Progressive Disease in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a prototype of chronic, progressive, and fibrotic lung disease. It has been considered rare, with an incidence estimated to 11.5 cases per 100 000

0 views
09 May, 2021
1 location

Examination of Pirfenidone (Esbriet ) Therapy in Coal Workers' Pneumoconiosis With Pulmonary Fibrosis

Examination of pirfenidone (Esbriet) therapy in coal workers' pneumoconiosis (black lung) with pulmonary fibrosis (scarring of the lung).

0 views
25 Jan, 2021
1 location

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Found 221 clinical trials