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Found 4457 clinical trials
Featured trial
Study to Assess the Efficacy Safety and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)  

Primary Objective: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former …

  • 662 views
  • 27 Sep, 2022
  • 58 locations
Featured trial
  • 0 views
  • 17 Sep, 2022
  • 117 locations
Featured trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of INCB099280 in participants with select solid tumors

  • 0 views
  • 19 Jun, 2022
  • 16 locations
Featured trial
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

This is a multicenter, open-label, dose-escalation/dose-expansion Phase 1 clinical study to investigate the safety, tolerability, PK profile, pharmacodynamics, and preliminary clinical efficacy of INCB106385 when given as monotherapy or in combination with INCMGA00012 in participants with selected CD8 T-cell-positive advanced solid tumors including SCCHN, NSCLC, ovarian cancer, CRPC, TNBC, bladder …

cancer of the ovary
cancer
bladder tumor
measurable disease
  • 36 views
  • 11 Jul, 2022
  • 19 locations
Featured trial
Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether FT218 is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.

excessive daytime sleepiness
sodium oxybate
somnolence
multiple sleep latency test
stimulant
  • 429 views
  • 10 Jul, 2018
  • 53 locations
Featured trial
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Advanced Non-Small Cell Lung Cancer With an FGFR Alteration Who Progressed on Previous Therapy (FIGHT 210) (FIGHT-210)

This is an open-label, single arm study to study the safety, efficacy and tolerability of Pemigatinib when used on participants with squamous or nonsquamous NSCLC with a documented FGFR1-3 mutations or fusions/rearrangement who have progressed on prior therapies and have no available standard treatment options

lung carcinoma
FGFR1
measurable disease
metastasis
  • 0 views
  • 22 Sep, 2022
  • 10 locations
Featured trial
Lung Nodules – Scheduled or Planned Biopsy

It's estimated that 1.5 million new cases of lung nodules are found per year in the United States. The goal in managing this condition is to rapidly identify and resect malignant nodules and avoid

  • 14 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Small cell lung cancer (SCLC) Receiving Zepzelca

People with SMALL CELL LUNG CANCER are asked to participate in a research study being conducted by Montefiore Medical Center.

lung carcinoma
  • 3 views
  • 06 Aug, 2021
  • 1 location
Featured trial
A Phase III Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ensifentrine over 24 Weeks in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease.

identical over the first 24 weeks. The 48-week subset will continue to assess long-term safety in this subset of patients.  Both studies will assess lung function, symptoms, and quality of life

  • 183 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Albuterol in Patients With Lymphangioleiomyomatosis

Background: Lymphangioleiomyomatosis (LAM) is a rare type of lung disease that occurs almost exclusively in women. In LAM, muscle tissue grows in the lungs and starts

lymphangioleiomyomatosis
  • 94 views
  • 22 Dec, 2020
  • 1 location