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Found 2 clinical trials
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

In this research study the investigators want to learn more about the safety of the study drug, PTC596 has when taken during radiation. The investigators also want to learn about the effects, if

renal function
anaplastic astrocytoma
seizure
astrocytoma
total resection
  • 2 views
  • 07 Oct, 2022
  • 9 locations
A Phase 2/3 Study to Evaluate the Efficacy and Safety of Unesbulin in Unresectable or Metastatic, Relapsed or Refractory Leiomyosarcoma (SUNRISELMS)

This study will compare the efficacy and safety of unesbulin plus dacarbazine versus placebo plus dacarbazine in participants with unresectable or metastatic, relapsed or refractory LMS who have received at least 1 prior line of systemic therapy.

systemic therapy
leiomyosarcoma
dacarbazine
  • 0 views
  • 18 Oct, 2022
  • 4 locations