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Found 53 clinical trials
An Implementation Study of Suicide Risk Management Among Discharged Psychiatric Patients

suicide intervention strategy. The study will recruit patients with psychotic symptoms and with major depressive disorder discharged from Shenzhen Kangning Hospital (SKH) in a Sequential Multiple

depressive disorder
  • 27 Apr, 2022
  • 1 location
R33: Levetiracetam in Early Psychosis

the hypotheses that adding levetiracetam will improve psychotic symptoms that are unresponsive to antipsychotic treatment and will protect the brain from atrophy (volume loss). .

  • 25 Nov, 2021
  • 1 location
Repetitive Transcranial Magnetic Stimulation in Early Psychosis and The Functional Connectivity Biotypes

which the patients present psychotic symptoms (positive symptoms, negative symptoms) and cognition deficits. Antipsychotics are often prescribed to treat these symptoms, but more than one third patients

  • 02 May, 2021
  • 3 locations
Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance Schizophrenia

Based on the hypothesis that low-frequency deep transcranial magnetic stimulation(dTMS) on anterior cingulate cortex ACC could down-regulate the glutamate level of ACC and regulate the acc-related functional network in patients with treatment resistance schizophrenia,this research plan to utilise multimodal functional magnetic imaging method(including structural MRI,resting-state functional magnetic resonance imaging and …

  • 23 Sep, 2021
  • 1 location
TMS for Symptom Reduction in Schizophrenia

To test the hypothesis that functionally navigated repetitive TMS stimulations to the prefrontal cortex (PFC) modulate aberrant cortical electrical activities at PFC circuitry. The TMS location of the PFC site will be individually localized by the symptom-related functional connectivity between PFC and symptom related areas (such as the auditory and …

  • 24 Feb, 2022
  • 1 location
Understanding of Psychotic Disorders in Children With 22q11.2DS (PremiCeS22)

The study PremiCeS22 will investigate the prodromal signals at the onset of psychotic disorders of children with 22q11.2 deletion syndrome

Accepts healthy volunteers
  • 23 Mar, 2022
  • 1 location
Effects of an Integrative Psychological Program in Bipolar Disorder

Bipolar disorder is related to a high level of personal, familial, social and economic burden. There is a need for feasible adjunctive psychological interventions to use in clinical practice as a complement of pharmacotherapy to enhance aspects that medication cannot reach. This project aims at develop and evaluate the impact …

psychiatric treatment
  • 22 Mar, 2022
  • 1 location
Glutamatergic Mechanisms of Psychosis and Target Engagement (SA1)

50 healthy volunteers (HV) will participate in 2 identical ketamine-induced pharmacoBOLD (phBOLD) sessions at least 7 days apart. On both days, clinical assessments will be performed following removal of the subject from the scanner. HV will be discharged home after clearance by the study physician. This study will assign ketamine …

Accepts healthy volunteers
  • 22 Mar, 2022
  • 1 location
COG-PSYCHO : Social Cognition and Psychotic Characteristics: Genetic and Phenomic Approach

dopamine pathways may be involved SC performance. Our endophenotype approach aimed to demonstrate that SC deficits are more severe in schizophrenia and BD or depression with psychotic symptoms (PBP) and

  • 24 Jun, 2021
  • 1 location
Using Digital Media Advertising to Reduce the Duration of Untreated Psychosis

There is compelling evidence that longer duration of untreated psychosis independently predicts negative outcomes. The proposal aims to explore whether targeted and proactive online outreach through search engine advertisements, coupled with engaging, informative, and interactive online resources, can effectively reduce the duration of untreated psychosis and facilitate earlier treatment initiation …

  • 18 Feb, 2022
  • 2 locations