Found 580 clinical trials
![A multicenter, randomized, double-blind, placebo-controlled, parallel-arm study to assess the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of negative symptoms of schizophrenia](/media/imagery/270525.svg)
A multicenter, randomized, double-blind, placebo-controlled, parallel-arm study to assess the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of negative symptoms of schizophrenia
The purpose of this research is to evaluate the efficacy, safety and tolerability of AVP-786 compared to placebo for the treatment of negative symptoms of schizophrenia. Negative symptoms of schizophrenia can include difficulty in displaying emotion through facial expressions, apathy (lack of interest), slowed speech production, loss of ability to …
- 0 views
- 05 Apr, 2021
- 1 location
A Phase IIIb Multi-Center, Open-Label, Mirror-Image, Trial in Adult Subjects with Schizophrenia Treated Prospectively for 6-months with Abilify MyCite®
To compare inpatient psychiatric hospitalization rates (proportion of subjects with ≥ 1 inpatient psychiatric hospitalizations) between the retrospective period (Months 1 to 3) while subjects are on oral standard-of-care antipsychotic treatment and the prospective period (Months 1 to 3) after the subjects switch to Abilify MyCite®.
- 26 views
- 23 Nov, 2020
- 1 location
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients with Schizophrenia and Recent Weight Gain While Taking Antipsychotic Medications
To assess the efficacy of miricorilant compared with placebo in reversing recent antipsychoticinduced weight gain (AIWG)
- 45 views
- 23 Nov, 2020
- 1 location
A Study to Evaluate the Safety, Tolerability, and Effect of Risperidone Extended-Release Injectable Suspension (TV-46000) for Subcutaneous Use as Maintenance Treatment in Adult and Adolescent Patients with Schizophrenia
The primary objective of the study is to evaluate the long-term safety and tolerability of TV-46000 administered in adult and adolescent patients with schizophrenia.
- 19 views
- 23 Nov, 2020
- 1 location
A phase II randomized, double-blinded, placebo-controlled parallel group trial to examine the efficacy and safety of BI 425809 once daily with adjunctive Computerized Cognitive Training over 12 week treatment period in patients with schizophrenia
This study tests whether BI 425809 together with brain training using a computer improves mental functioning in patients with schizophrenia.
- 51 views
- 23 Nov, 2020
- 1 location
Study Seeking Patients with Schizophrenia
Study Seeking Patients with Schizophrenia
- 0 views
- 07 Nov, 2020
- 6 locations
Schizophrenia and Schizoaffective Disorders Study
Schizophrenia and Schizoaffective Disorders Study
- 1456 views
- 08 Nov, 2020
- 1 location
A Washington University research study seeks participants struggling with weight and mental illness.
The research study is designed to test how well text messaging, in addition to one-on-one meetings with a health coach, can help an individual identify and reach his or her personal health goals (including managing weight). There will be 5 study visits with a health coach to review health-related topics …
- 212 views
- 23 Nov, 2020
- 1 location
Study of Efficacy of PEAR-004 in Schizophrenia.
The purpose of the study is to determine in patients currently being administered antipsychotic pharmacotherapy whether PEAR-004 can further reduce symptoms of schizophrenia as measured by the Positive and Negative Syndrome Scale (PANSS). The overall rationale for the study is to assess the first prescription digital therapeutic (PDT) in schizophrenia …
- 31 views
- 22 Dec, 2020
- 1 location
A Study to Evaluate the Effects of Basmisanil in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS) Treated With Antipsychotics.
This multicenter study will assess the effects of 24 weeks of basmisanil treatment on cognition and functioning of stable schizophrenia participants treated with antipsychotics.
- 22 views
- 22 Dec, 2020
- 1 location