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Found 94 clinical trials
The AP-GELP Study: A Clinical Trial on the Effects of Apremilast in Female Genital Erosive Lichen Planus

Genital erosive lichen planus (GELP) is a chronic inflammatory disease causing painful genital sores and scarring in women. Treatment options are limited and often unsatisfactory. This trial will study the effects of treatment with apremilast and quality of life and sexual function in women with GELP.

apremilast
  • 0 views
  • 26 Jan, 2021
  • 1 location
Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients With Leukocyte Adhesion Deficiency Type 1 (LAD1) Who Have Inflammatory Pathology

Background The disease leukocyte adhesion deficiency type 1 (LAD1) affects white blood cells. Those are immune system cells. In people with LAD1, white blood cells do not properly communicate with the rest of the body. This causes uncontrolled inflammation, particularly in the gums. People with LAD1 can get frequent infections …

  • 21 views
  • 25 Jan, 2021
  • 1 location
An Open-Label Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

Background Crohn s disease (CD) is an inflammatory bowel disease. It causes inflammation of the gut. Symptoms may include diarrhea, abdominal pain, fatigue, weight loss and malnutrition. CD has no cure, but symptoms can sometimes be controlled with medicine. Researchers want to see if it is safe to treat CD …

immunomodulators
mesalamine
ustekinumab
vedolizumab
diarrhea
  • 53 views
  • 02 Mar, 2021
  • 1 location
A Study of Apremilast Use and Effectiveness in Patients With Psoriatic Arthritis in The Netherlands

This is a multicenter, prospective, non-interventional, observational single arm study. 100 patients will be recruited in the Netherlands over a one year period. In all cases, the decision to treat the patient with apremilast will be made prior to the decision to enter the subject into this study. Treatment will …

apremilast
  • 0 views
  • 27 Jan, 2021
  • 12 locations
Study on the Safety for the Newborn of the Use of Biologics During Pregnancy by Mothers Affected by Autoimmune Diseases

The goal of the study is to evaluate the effects on the offspring and therefore the safety of using biologic agents during pregnancy and their eventual consequences on children. The effects considered are divided into peri-partum and more long-term effects. Demonstration of safety in children born from mothers who received …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Investigating the Utilisation and Effectiveness of Originator and Biosimilar Anti-TNF Agents

An observational study investigating the utilisation and effectiveness of originator and biosimilar anti-TNF agents in patients with rheumatoid arthritis, psoriatic arthritis, or ankylosing

biosimilar
tumor necrosis factor
rheumatoid arthritis
arthritis
spondylitis
  • 821 views
  • 22 Jan, 2021
  • 22 locations
A Worldwide Survey on the Understanding of Psoriatic Disease Among Patients With Psoriasis and Psoriatic Arthritis

The study is a Worldwide Survey on the Understanding of Psoriatic Disease among Patients with Psoriasis and Psoriatic Arthritis.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Psoriasis Longitudinal Assessment and Registry

receiving other therapies, such as non-biologic and other biologic agents. The registry also evaluates patient and disease characteristics, including patient-reported assessment of psoriatic arthritis (PsA

ustekinumab
cyclosporine
biological drug
ixekizumab
psoralen
  • 4031 views
  • 27 Feb, 2021
  • 483 locations
Korean College of Rheumatology Biologics Registry

We plan to establish a nationwide Biologics Registry (in the form of an inception cohort) to study the safety profiles in rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis

DMARD
rheumatoid arthritis
biological drug
ankylosing spondylitis
rheumatic diseases
  • 35 views
  • 25 Jan, 2021
  • 1 location
One-year Persistence to Treatment of Participants Receiving Flixabi or Imraldi: a French Cohort Study

: Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS), Psoriatic Arthritis (PsA), Crohn's Disease (CD) [adults and children] and Ulcerative Colitis (UC) [adults for both treatments and children only for

biosimilar
ulcerative colitis
rheumatoid arthritis
ulceration
ankylosing spondylitis
  • 38 views
  • 24 Jan, 2021
  • 8 locations