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Found 94 clinical trials
Validation of the PsASon ULtrasound Scores in Patients With Psoriatic Arthritis Undergoing TReatment With Apremilast

The main purpose of this study is to validate the ultrasound scores PsASon22 and PsASon13 in patients with active psoriatic arthritis undergoing a treatment with Apremilast.

arthritis
apremilast
dactylitis
enthesitis
methotrexate
  • 0 views
  • 26 Jan, 2021
  • 1 location
Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial

SPEED is a three arm interventional trial nested within a cohort (Trials Within Cohorts or TWiCs design). This tests more aggressive early therapy in patients newly diagnosed with moderate to severe PsA. Arm 1 will receive standard step up therapy in the cohort and act as the control group. Arm …

sulfasalazine
leflunomide
tumour necrosis
platelet count
adalimumab
  • 2 views
  • 24 Jan, 2021
  • 1 location
Tofacitinib for Reduction of Spinal Inflammation in Patients With Psoriatic ArthritiS PresenTing With Axial InvOlvement

To evaluate the efficacy of Tofacitinib in reducing inflammation in the sacroiliac joints and spine on magnetic resonance imaging (MRI) in patients with active Psoriatic Arthritis (PsA) with

arthritis
ankylosing spondylitis
NSAID
spondylitis
tofacitinib
  • 0 views
  • 05 Feb, 2021
  • 19 locations
A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic Arthritis

The purpose of this study is to assess the safety of subcutaneous (SC) golimumab in participants with active Ankylosing Spondylitis (AS) or Psoriatic Arthritis (PsA) over 24 weeks.

golimumab
arthritis mutilans
peripheral arthritis
steroidal anti-inflammatory drugs
methotrexate
  • 96 views
  • 02 Mar, 2021
  • 12 locations
Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNF -Inhibitor Treatment

The purpose of this study is to compare the safety and efficacy of secukinumab and ustekinumab in patients with active psoriatic arthritis who showed failure to previous TNF-inhibitor treatment

  • 0 views
  • 29 Jan, 2021
  • 3 locations
A Study to Investigate Efficacy Tolerability and Safety of ABY-035 in Patients With Active Psoriatic Arthritis

This is a Phase II, prospective, multicenter, randomized, double-blind, placebo-controlled, dosefinding trial in parallel-groups with primary endpoint at Week 16 (visit V9) to investigate the efficacy, tolerability, safety, pharmacokinetics and immunogenicity of ABY-035 in adult patients with PsA.

  • 0 views
  • 30 Jan, 2021
  • 1 location
BIOTIPRA: BIOmarker-guided Treatment Decisions In Psoriatic and Rheumatoid Arthritis

TNFi drugs remain the most prescribed first-line biologics for patients with rheumatoid arthritis (RA) and Psoriatic Arthritis (PsA). However, up to 40% of RA patients fail to respond to TNFi

  • 0 views
  • 27 Jan, 2021
  • 8 locations
An Efficacy Study of Secukinumab in Plaque Psoriasis Patients With Subclinical Psoriatic Arthritis as Measured by Musculoskeletal Ultrasound

psoriasis patients. This study will be the first randomized trial of a biologic therapy versus placebo in participants with plaque psoriasis and subclinical psoriatic arthritis, using musculoskeletal

  • 0 views
  • 27 Jan, 2021
  • 1 location
PsA Secukinumab XCT Structural Progression Study

Psoriatic arthritis is related with chronic inflammation and progressive radiographic damages, and it in turn lead to disability and loss in function-ability. Recent advance in treatment pathway

arthritis
anti-rheumatic drugs
DMARD
secukinumab
  • 7 views
  • 05 Feb, 2021
  • 1 location
GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA (GOLMEPsA)

An investigator-initiated double-blind, parallel-group randomised controlled trial of GOLimumab and Methotrexate versus Methotrexate in very early PsA using clinical and whole body MRI outcomes.

  • 0 views
  • 23 Jan, 2021
  • 1 location