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Found 94 clinical trials
An Extension Study of Subcutaneous Secukinumab in Patients With Juvenile Psoriatic Arthritis (JPsA) and Enthesitis Related Arthritis (ERA)

Optional open label, roll over extension study to investigate the efficacy and safety of secukinumab treatment in Juvenile Idiopathic Arthritis (JIA) subtypes of Juvenile Psoriatic Arthritis

arthritis
  • 1 views
  • 27 Jan, 2021
  • 21 locations
A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol)

The purpose of the study is to assess systemic certolizumab pegol (CZP) exposure, the formation of anti-CZP antibodies and safety of CZP across the course of pregnancy in study participants with chronic inflammatory diseases.

certolizumab pegol
purified protein derivative
bacillus calmette-guerin
tuberculosis
cimzia
  • 54 views
  • 24 Feb, 2021
  • 9 locations
COVID-19 CoronaVac in Patients With Autoimmune Rheumatic Diseases and HIV/AIDS

Patients with chronic rheumatic diseases (such as systemic lupus erythematosus [SLE], rheumatoid arthritis [RA], ankylosing spondylitis [AS], juvenile idiopathic arthritis [JIA], poly/dermatomyositis [PM/DM], systemic sclerosis [SSc], systemic vasculitis, and primary Sjgren's syndrome [pSS]) are particularly susceptible to infectious diseases due to autoimmune disorder itself and its treatment (immunosuppressive therapies). Similarly, …

  • 0 views
  • 04 Mar, 2021
  • 1 location
A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteritis

The primary purpose of this study is to evaluate the efficacy of guselkumab compared to placebo, in combination with a 26-week glucocorticoid (GC) taper regimen, in adult participants with new-onset or relapsing giant cell arteritis (GCA).

  • 0 views
  • 26 Feb, 2021
  • 32 locations
A Study of Guselkumab in Participants With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy of guselkumab in participants with active lupus nephritis (LN).

mycophenolic acid
antinuclear antibody
prednisone
mammogram
glucocorticoids
  • 0 views
  • 25 Feb, 2021
  • 61 locations
Psoriatic Arthritis and Psoriasis Treatment Decision Aid

The purpose of this study is to create and test a patient decision aid that facilitates the shared decision-making process when patients with psoriasis and/or psoriatic arthritis are starting or

biosimilar
arthritis
psoriasis
DMARD
psoriasis treatment
  • 0 views
  • 14 Feb, 2021
  • 1 location
CBD Treatment in Hand Osteoarthritis and Psoriatic Arthritis.

A randomized, placebo-controlled trial with blinded outcome assessments will be conducted to evaluate the efficacy and safety of CBD in patients with Hand-OA and PsA during a 12-week treatment period.

vasectomy
arthritis
oophorectomy
human chorionic gonadotrophin
hysterectomy
  • 17 views
  • 27 Jan, 2021
  • 1 location
Molecular Effects of Apremilast in the Synovium of Psoriatic Arthritis Patients

This study assess the genomics profiles in synovial biopsies obtained prior to, and 24 weeks after an immunomodulator agent (Apremilast) in patients with active psoriatic arthritis who are naive

  • 0 views
  • 27 Jan, 2021
  • 1 location
Efficacy And Safety Of Tofacitinib In Chinese Subjects With Active Psoriatic Arthritis

This is a 6 month study investigating the effectiveness and safety of tofacitinib in treating signs and symptoms and improving physical function in Chinese patients with active psoriatic

arthritis
plaque psoriasis
psoriasis
DMARD
rheumatic diseases
  • 16 views
  • 18 Feb, 2021
  • 44 locations
TNF and IL23 Blocking Agents Gene Expression Ratios in the Psoriatic Arthritis Synovium_(TIGERS) Study

) in patients with active psoriatic arthritis despite a treatment with a conventional synthetic DMARDs (such as methotrexate).

adalimumab
arthritis
corticosteroids
tumor necrosis factor
methotrexate
  • 1 views
  • 24 Jan, 2021
  • 2 locations