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Found 18 clinical trials
Featured trial
A national, multi-center, randomized, double-blind, 4 arm, 8 week study in subjects with psoriasis vulgaris on the non-scalp regions of the body (trunk and/or limbs)

A national, multi-center, randomized, double-blind, 4 arm, 8 week study in subjects with psoriasis vulgaris on the non-scalp regions of the body (trunk and/or limbs)

  • 164 views
  • 08 Nov, 2020
  • 1 location
None
Phase IV Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Psoriasis in Adults

psoriasis vulgaris in adults. Approximately 2000 adult participants with mild to moderate stable psoriasis vulgaris will be enrolled and they will use the Benvitimod cream at the skin with psoriasis for 12

psoriasis vulgaris
  • 0 views
  • 09 Oct, 2021
  • 1 location
None
Predicting Inflammatory Skin Disease Response to IL-23 Blockade

This study examines the effect of IL-23 blockade with Tildrakizumab on the immune cells of psoriatic skin lesions.

  • 0 views
  • 26 Feb, 2021
  • 1 location
None
Secukinumab Therapy for the Treatment of Moderate to Severe Plaque Psoriasis With Response Monitoring Using Optical Coherence Tomography (OCT).

This is a phase IV, single-center, open label, single arm study in which a group of 30 subjects with moderate to severe plaque psoriasis will receive secukinumab therapy. Non-invasive imaging with optical coherence tomography (OCT) will be used to monitor the resolution of psoriatic plaques with treatment in comparison to …

psoriasis
secukinumab therapy
oophorectomy
tubal ligation
prophylaxis
  • 22 views
  • 11 Sep, 2021
  • 1 location
None
An Explorative Psoriasis Biomarker Study

Plaque psoriasis may be an ideal model disease to explore potential therapeutic effects of immunosuppressive agents, given the easy accessibility of inflammatory lesions. In this study, the applicability of a systems dermatology approach is investigated in order to better assess the efficacy of psoriasis treatments at an early clinical stage. …

  • 0 views
  • 24 Jun, 2021
  • 1 location
None
Pilot Study of Traditional Chinese Medicine (Qing-Re-Liang-Xue Decoction) as Complementary Medicine for Psoriasis Vulgaris of Blood-heat Syndrome.

pathogenesis of psoriasis. We used Qingre Liangxue Recipe Granules to observe the treatment of 31 patients with blood-heat type psoriasis vulgaris, and found that the PASI index of the patients after treatment

  • 0 views
  • 16 Aug, 2021
  • 1 location
None
Therapeutic Drug Monitoring of Guselkumab in Psoriasis Patients

Biologic such as guselkumab are currently the most effective treatment option for patients with moderate to severe psoriasis. But they are costly for healthcare systems and still described according to a 'one dose fits all' dosing regimen, leading to potential over- and undertreatment. In this study we aim to investigate …

psoriasis
  • 1 views
  • 24 Jan, 2021
  • 6 locations
None
Therapeutic Drug Monitoring of Brodalumab in Psoriasis Patients (BIOLOPTIM-BRO)

Biologics, such as brodalumab, are currently the most effective treatment option for patients with moderate-to-severe psoriasis. But they are costly for health care systems and prescribed according to a 'one dose fits all' dosing regimen, leading to potential over- and undertreatment. Within this study we aim to investigate the predictive …

psoriasis
brodalumab
biologics
  • 5 views
  • 24 Jan, 2021
  • 6 locations
None
Therapeutic Drug Monitoring of Secukinumab in Psoriasis Patients.

Biologics such as secukinumab are currently the most effective treatment option for patients with moderate to severe psoriasis. But they are costly for healthcare systems and still described according to a'one dose fits all' dosing regimen, leading to potential over-and undertreatment. In this study we aim to investigate the predictive …

psoriasis
biologics
  • 0 views
  • 26 Jan, 2021
  • 7 locations
None
Efficacy and Safety of Brodalumab Compared With Guselkumab in the Treatment of Plaque Psoriasis After Inadequate Response to Ustekinumab

The trial investigates the efficacy and safety of brodalumab against guselkumab in treatment for patients with moderate-to-severe plaque psoriasis who still have some remaining symptoms after ustekinumab treatment.

plaque psoriasis
ustekinumab
guselkumab
  • 0 views
  • 19 Oct, 2021
  • 71 locations