Found 88 clinical trials
Rituximab and RASi in Patients With IgAN
A study to evaluate safety and activity in treatment of IgAN patients using Rituximab in combination with RASi(ACEI and/or ARB) compared with RASi.
- 0 views
- 15 Oct, 2021
- 1 location
PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant
This is a phase III, multicenter, randomized, open label, clinical trial to test that hypothesis that plasmapheresis plus rituximab prior to kidney transplantation can prevent recurrent FSGS in children and adults.
- 102 views
- 12 Feb, 2022
- 14 locations
Imaging vs. no Testing in Asymptomatic High-risk Diabetic Patients
The aim of our study was to evaluate 1- and 3-year outcome of alternative imaging strategies in asymptomatic high-risk diabetic patients: functional stress echocardiography combined with coronary flow reserve (CFR) and strain imaging, or computed tomography (CT) angiography with direct visualization of coronary arteries, and no testing at all.
- 0 views
- 29 Aug, 2021
- 1 location
lncRNAs as a Biomarker to Assess the Therapeutic Impact of Oral Absorbent Probiotics in CKD Patients With PAD
Participants with chronic kidney disease (CKD) are at a higher risk of developing atherosclerotic peripheral artery disease (PAD). Retention of uremic toxins such as indoxyl sulfate (IS), p-cresyl sulfate (PCS) and trimethylamine N-oxide (TMAO) during CKD is detrimental to endothelial and vascular function and can predispose to the development and …
- 0 views
- 15 Mar, 2021
- 1 location
Low Doses of Aspirin in the Prevention of Preeclampsia (ASAPP)
Preeclampsia (PE) is a morbid and potentially lethal complication of pregnancy and is more common in women with specific risk factors. Aspirin (ASA) is currently the only prophylactic therapy for preeclampsia in high-risk women to be recognized by the US Preventive Task Force and should be initiated early in the …
- 90 views
- 18 Feb, 2022
- 1 location
Study of Oral Uremic Toxin Absorbent and Probiotics to Retard the Progression of Chronic Kidney Disease
In patients with chronic kidney disease (CKD), uremic toxins accumulate when kidney function declines. Those uremic toxins had a greater affinity to circulating proteins are called "protein bound uremic toxins, PBUT." Apart from traditional small or middle molecule uremic toxins, the PBUTs can be rarely eliminated using traditional renal replacement …
- 2 views
- 03 Apr, 2021
- 1 location
Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy
The aim of this cross-over trial is to assess aliskiren, a direct renin inhibitor, as a novel treatment to block complement activation in the kidneys and thereby attenuate renal disease and stabilize or improve kidney function and compare it to the currently used treatment with the angiotensin converting enzyme inhibitor, …
- 17 views
- 06 Apr, 2023
- 1 location
Per-protocol Repeat Kidney Biopsy in Incident Cases of Lupus Nephritis (REBIOLUP)
Lupus nephritis (LN) is one of the most severe complications of systemic lupus erythematosus (SLE). Among people living with SLE, 35-60% will develop LN during the course of the disease. This complication is one of the factors that contribute to deterioration of the renal function. Some centres perform kidney biopsies …
- 0 views
- 07 Jul, 2022
- 1 location
SVF (Adipose Tissue Derived MSC) Based Therapy for CKD. (StemCell&CKD)
To assess the safety of stromal vascular fraction (Autologous Non Expanded ADSC) injection to patients with Chronic Kidney Disease. To assess the efficacy of stromal vascular fraction (Autologous Non Expanded ADSC) injection to patients with Chronic Kidney Disease.
- 68 views
- 06 Feb, 2022
- 1 location
Proteinuria in Pre and Post Transplant
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney
- 1 views
- 01 Oct, 2023
- 1 location