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Found 88 clinical trials
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Background Membranous nephropathy is associated with damage to the walls of the glomeruli, the small blood vessels in the kidneys that filter waste products from the blood. This damage causes leakage of blood proteins into the urine and is associated with low blood protein levels, high blood cholesterol values, and …

edema
cyclosporine
blood tests
proteinuria
blood test
  • 243 views
  • 12 Sep, 2023
  • 2 locations
Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care

Pre-eclampsia (PE) is a pregnancy-associated syndrome of variable severity, classically defined by the combination of hypertension and proteinuria in a previously non-hypertensive or proteinuric

diabetes
hypertension
proteinuria
  • 0 views
  • 10 Oct, 2021
  • 2 locations
DAPAgliflozin for Renal Protection in Heart Transplant Recipients (DAPARHT)

. Secondary objectives are to assess the impact of treatment on i) weight, ii) glucose homeostasis, iii) proteinuria, iv) the number of rejections, and (v) safety and tolerability. As exploratory outcomes

diabetes
cancer
proteinuria
  • 0 views
  • 07 Oct, 2022
  • 1 location
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children (FSGS pediatric)

common complication of nephrotic syndrome and found to bring about improvement not only with the dyslipidemic condition but the nephrotic condition (e.g, proteinuria and hypoproteinemia).

primary focal segmental glomerulosclerosis
alternative therapies
remission
plasma cholesterol
low density lipoprotein
  • 36 views
  • 20 Apr, 2022
  • 10 locations
Obinutuzumab in Primary MN (ORION)

spend most of their live with nephrotic range proteinuria (rituximab-dependent patients). Obinutuzumab is a humanized monoclonal antibody with enhanced B cell-depleting potential. Due to humanization

rituximab
proteinuria
kidney biopsy
renal function
nephropathy
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function

Proteinuria % regulatory T-cells in circulation NODAT [New Onset Diabetes mellitus After Transplant], hypertension and malignancy Tolerance measured by gene

chronic disease
renal function test
proteinuria
immunosuppression
immunosuppressive agents
  • 3 views
  • 26 Feb, 2022
  • 1 location
Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF (OBILUP)

response at week 52; proteinuria < 0.8g/g at week 52; extrarenal flares; response as defined by a >4 points reduction in SELENA-SLEDAI score at week 52. To

hydroxychloroquine
renal function
nephritis
lupus
induction therapy
  • 0 views
  • 11 Apr, 2023
  • 1 location
Belimumab With Rituximab for Primary Membranous Nephropathy (REBOOT)

The primary objective of this study is to evaluate the effectiveness of belimumab and intravenous rituximab co-administration at inducing a complete remission (CR) compared to rituximab alone in participants with PM. Background Primary membranous nephropathy (MN) is among the most common causes of nephrotic syndrome in adults. MN affects individuals …

monoclonal antibody
remission
lupus
rituximab
proteinuria
  • 347 views
  • 02 Sep, 2023
  • 14 locations
Steroids Therapy in IgA Nephropathy With Crescents

This prospective, randomized, controlled, multi-center clinical trial will evaluate the effect and security of steroids therapy for patients of IgA nephropathy with crescents.

nephropathy
prednisone
  • 0 views
  • 11 Jun, 2021
  • 1 location
Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy (CHASAP)

A randomized clinical trial to assess the efficiency of acetylsalicylic acid (aspirin) 150 mg/day started before 20 weeks of gestation in the prevention on maternal and fœtal complications in pregnant women with chronic hypertension.

hypertension
aspirin
  • 0 views
  • 21 Apr, 2022
  • 10 locations