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Found 112 clinical trials
Pentoxifylline in Diabetic Kidney Disease

Pentoxifylline (PTX) is a medication that has been on the market since 1984 for use in disease in the blood vessels of the legs. There is some preliminary information that it may protect the kidneys from damage due to diabetes and other diseases. "Pentoxifylline in Diabetic Kidney Disease" is a …

nephropathy
diabetic nephropathy
pentoxifylline
diabetes
  • 6 views
  • 16 Mar, 2021
  • 6 locations
Aspirin to Target Arterial Events in Chronic Kidney Disease

This study aims to find out whether people with chronic kidney disease [CKD] should take low dose aspirin to reduce the risk of first heart attack or stroke (cardiovascular disease [CVD]). CKD is common and is associated with an increased risk of CVD. CVD is caused by small blood clots …

primary prevention
nephropathy
aspirin
myocardial infarction
clot
  • 0 views
  • 23 Jan, 2021
  • 1 location
HMG-CoA Reductase add-on in Chronic Kidney Disease Patients With Proteinuria

This study is to evaluate the renal function of HMG-CoA reductase add-on in chronic kidney disease patients with proteinuria.

  • 0 views
  • 26 Jan, 2021
  • 11 locations
Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies (PROERCAN01)

patients will receive angiotensin converting enzyme inhibitors, while the other half will not receive them. Renal function, proteinuria and cardiovascular events will be follow up during a three year

amlodipine
renin
renal function
ace inhibitor
nephropathy
  • 20 views
  • 23 Jan, 2021
  • 1 location
Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease

shown to improve endothelial function, as well as decrease CV mortality and proteinuria. The specific biochemical pathways that produce these pharmacological effects for MR antagonists, however, are

nephropathy
proteinuria
dialysis
chronic kidney disease
  • 39 views
  • 24 Jan, 2021
  • 1 location
Intensive Medical Treatment for Nephropathy Caused by Type 2 Diabetes With Hypertension

To observe the effect of intensive medical treatment for type 2 diabetic patients with hypertension: to discover whether or not intensive medical treatment improves proteinuria, and the

valsartan
diabetes
nephropathy
type 2 diabetes mellitus
hypertension
  • 19 views
  • 07 Nov, 2020
  • 1 location
Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury

The purpose of this study is to test the hypothesis that isosorbide mononitrate prevents deterioration of renal function in patients receiving anti-angiogenic therapies that target vascular endothelial growth factor (VEGF).

  • 0 views
  • 26 Jan, 2021
  • 1 location
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Background Membranous nephropathy is associated with damage to the walls of the glomeruli, the small blood vessels in the kidneys that filter waste products from the blood. This damage causes leakage of blood proteins into the urine and is associated with low blood protein levels, high blood cholesterol values, and …

active treatment
cyclosporine
immunosuppressive agents
blood proteins
kidney biopsy
  • 236 views
  • 12 May, 2021
  • 2 locations
Effects of Probiotics and Fibers on Albuminuria in Persons With Type 1 Diabetes

The primary objective is to assess the impact of three months' treatment with pre-/probiotic mix on markers of nephropathy and other comorbidity related to diabetes. A double blinded, randomized, placebo-controlled crossover, single-centre study including 46 patients with type 1 diabetes and albuminuria. The treatment period is 2 x 12 weeks …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Calcitriol in the Treatment of Immunoglobulin A Nephropathy

nephropathy. Forty patients with biopsy-proven IgA nephropathy will be recruited. They will be randomized to Calcitriol for six months or no treatment. Proteinuria, renal function, serum and urinary

immunoglobulin g
renal function
nephropathy
immunoglobulin a
calcitriol
  • 30 views
  • 07 Nov, 2020
  • 1 location