Found 106 clinical trials
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Multi-country trial
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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For all genders
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Currently Recruiting
AURONA - An Open-Label Dose-Exploration Cohort Study Evaluating the Efficacy and Safety of Voclosporin in Achieving Complete or Partial Remission of Proteinuria in Subjects with Focal Segmental Glomerulosclerosis
proteinuria after 24 weeks of therapy in subjects with focal segmental glomerulosclerosis (FSGS). - To assess the safety and tolerability of VCS over 24 weeks in subjects with
- 76 views
- 23 Nov, 2020
- 2 locations
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Multi-country trial
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Phase 2 trial
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Accepting adults
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For all genders
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Nephrology
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Currently Recruiting
ALN-CC5-005: A Phase 2, Randomized, Double-blind, Placebo-controlled Study of Cemdisiran in Adult Patients with IgA Nephropathy
; blood pressure, kidney function, degree of hematuria, and proteinuria will be measured. Patients will not receive study drug (cemdisiran or placebo) during this time. The standard of care is
- 99 views
- 23 Nov, 2020
- 2 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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For all genders
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Currently Recruiting
Kidney Disease in Type 2 Diabetics
Kidney Disease in Type 2 Diabetics
- 1306 views
- 25 Mar, 2021
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Nephrology
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Currently Recruiting
A Crossover Pilot Study of the Effect of Amiloride on Proteinuria
This cross-over study is designed to test the hypothesis that amiloride will reduce urinary protein excretion and protect the kidney from rapid progression in proteinuric kidney disease.
- 3 views
- 23 Jan, 2021
- 2 locations
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Phase 2 trial
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Accepting pediatric ages
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Accepting Seniors
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10s of participants
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An interventional trial
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For all genders
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Nephrology
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Currently Recruiting
An Open Labeled Pilot Study of Atorvastatin in Systemic Lupus Erythematosus
The aim of this study is to to determine whether atorvastatin 40mg per day is effective in the treatment of SLE.
- 19 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Salvage Therapy With Sunitinib Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer
Sunitinib shows anti-tumor activity in a variety of human non-small cell lung tumor ex vivo models. Many Phases II and III clinical trials of sunitinib in several solid tumors are completed or still ongoing. So far, the efficacy of sunitinb has been confirmed by the phase III trial for imatinib-resistance …
- 2 views
- 08 Nov, 2020
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Feasibility of Low Energy Diet in HFpEF and Type 2 Diabetes
Open, Single arm intervention, feasibility study
- 0 views
- 23 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Nephrology
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Currently Recruiting
Comprehensive Management of Diabetic Patients With Renal Impairment : Impact on Blood Pressure and Glycemic Control
Diabetes is the leading cause of end-stage renal disease in developed countries. Hypertension and metabolic control are known to affect the progression of renal deficiency and patient's outcome. Our project aims at implementing a multidisciplinary and systematic approach of diabetic patients with renal deficiency, and at evaluating the impact of …
- 10 views
- 07 Nov, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients
The objective of this study is to examine the effect on allograft function and histology of converting African American renal transplant recipients with chronic allograft nephropathy (CAN) from a tacrolimus-based regimen to a sirolimus-based maintenance immunosuppression regimen. The investigators hypothesize that the conversion from tacrolimus to sirolimus in African American …
- 20 views
- 08 Nov, 2020
- 1 location
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Azithromycin in Post Diarrheal Haemolytic and Uremic Syndrome
Post diarrheal hemolytic and uremic syndrome (D+HUS) is the first etiology of acute renal failure in children less than 5 years old in France. Previous works highlighted a mortality rate of 2 % and a prevalence of renal sequelae at one year after D+HUS onset in 25 % of patients …
- 0 views
- 23 Jan, 2021
- 1 location