prostate specific antigen Clinical Research Trials

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Found 154 clinical trials

featured

The study will examine the effects that Metformin Hydrochloride has on Prostate Specific Antigen levels in men with Prostate Cancer.

70 views
23 Nov, 2020
1 location

featured

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

196 views
08 Nov, 2020
1 location

MRI Versus PSA in Prostate Cancer Screening

clinically-significant prostate cancer (defined as Gleason score 7 on prostate biopsy) compared with prostate cancer screening using prostate-specific antigen (PSA). The current paradigm of prostate

prostate cancer screening

biopsy of prostate

prostate specific antigen

multiparametric magnetic resonance imaging

27 views
08 Nov, 2020
1 location

Prostate Cancer Screening and Dietary Heterocyclic Amines in African American Men

RATIONALE: Screening may help doctors find prostate cancer sooner, when it may be easier to treat. The amount of heterocyclic amines in the diet may affect prostate cancer screening results and the risk of prostate cancer. PURPOSE: This phase II trial is studying prostate cancer screening and dietary heterocyclic amines …

prostate cancer screening

25 views
07 Nov, 2020
2 locations

Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer

RATIONALE: Androgens can cause the growth of prostate cancer cells. Hormone therapy, such as cyproterone acetate may stop the adrenal glands from making androgens. Sometimes the tumor may not need treatment until it progresses. In this case, observation may be sufficient. It is not yet known whether giving cyproterone acetate …

tumor progression

endocrine therapy

androgens

gonadotropin

hormone therapy

3 views
07 Nov, 2020
1 location

Study Comparing MRI/Ultrasound Fusion-guided Prostate Biopsy Versus Systematic Transrectal Ultrasound-guided Biopsy

Patients will be submitted to a multiparametric MRI examination of the prostate. Subsequently, all participants will be randomized (1:1) into both study arms. In study arm A patients will be submitted to the gold-standard which comprises systematic transrectal ultrasound-guided prostate biopsy. In study arm B patients will be submitted to …

biopsy of prostate

transrectal ultrasound

multiparametric magnetic resonance imaging

0 views
08 Nov, 2020
1 location

Docetaxel Compared With Observation in Treating Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving docetaxel after surgery may kill any tumor cells that remain after surgery. Sometimes, after surgery, the tumor may not …

immunological adjuvant

tumor cells

prostatectomy

docetaxel

35 views
07 Nov, 2020
5 locations

PSMA-PET Registry for Recurrent Prostate Cancer

This study aims to institute a province-wide registry leveraging the availability of a new Positron Emission Tomography tracer, [18F]-DCFPyL and PET expertise across Ontario centers to improve our ability to characterize patterns of recurrence and personalize therapies in men with recurrent prostate cancer after primary treatment.

prostatectomy

bone scan

positron emission tomography

ct scan

karnofsky performance status

50 views
11 Oct, 2020
8 locations

Androgen Deprivation Therapy in Treating Patients With Prostate Cancer

RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy may stop the adrenal glands from making androgens. PURPOSE: This randomized phase III trial is studying how well androgen deprivation therapy works in treating patients with prostate cancer.

orchiectomy

androgens

antiandrogen therapy

antiandrogens

androgen suppression