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Found 628 clinical trials
Featured trial
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

This study will determine if a dexamethasone mouth rinse can reduce the risk of developing oral chronic graft-versus-host disease (cGVHD) in patients who have undergone a bone marrow (stem cell) transplant procedure. cGVHD is a common complication of stem cell transplantation, resulting from the donor cells attacking the transplant recipient's …

graft versus host disease
graft-versus-host disease
  • 160 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Adolescent BV - Impact of the vaginal microbiome on topical HIV pre-exposure prophylaxis (PrEP)

Through this study, we hope to learn how healthy bacteria and bacteria associated with a vaginal infection called bacterial vaginosis (BV) affect how PrEP works in women. BV is a common infection in young women that causes itching, odor, vaginal discharge, and inflammation. Women with BV may be at increased …

sexually transmitted infections
  • 202 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Haplo-identical Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using Peripheral Blood Stem Cells and Post-Transplant Cyclophosphamide for GVHD Prophylaxis

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MD) cause serious blood problems. Stem cell transplants using bone marrow or blood plus chemotherapy can help. Researchers want to see if using peripheral blood stem cells (PBSCs) rather than bone marrow cells works too. PBSCs are easier to collect and have …

myelodysplastic syndrome (mds)
anemia
myelodysplastic syndromes
anemia studies
aplastic anemia
  • 75 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

Background: Cord blood is blood that is taken from the umbilical cord and placenta of healthy newborns after childbirth. The cord blood collected from a baby is called a cord blood unit. Cord blood units are stored frozen in public cord blood banks. About 10,000 cord blood transplants have been …

myelodysplastic syndrome (mds)
anemia
myelodysplastic syndromes
anemia studies
aplastic anemia
  • 79 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications

Background: Cord blood transplants can treat cancers and other diseases in children and adults. The U.S. Food and Drug Administration (FDA) requires cord blood to be collected and stored under certain safety standards. However, most available cord blood units were collected before the FDA set these standards. These units may …

myelodysplastic syndrome (mds)
anemia
myelodysplastic syndromes
anemia studies
aplastic anemia
  • 57 views
  • 22 Dec, 2020
  • 1 location
Prophylaxis of Post-ERCP Acute Pancreatitis (PEPPER)

This study aims to compare indomethacin and the combination of indomethacin and aggressive lactated Ringer infusion in terms of efficacy in preventing post-ERCP acute pancreatitis (PEP).

  • 0 views
  • 04 Jun, 2022
  • 1 location
CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia) (CiproPAL)

ciprofloxacin prophylaxis in the reduction of infection during the induction phase of treatment for paediatric Acute Lymphoblastic Leukaemia within the ALLTogether-1 Trial. To evaluate the impact of

  • 0 views
  • 25 Jul, 2022
  • 1 location
Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis (Bio-CHIC)

This study is testing whether stratification of the patients according to biological risk factors for different treatment groups will improve the outcome of patients with clinically high diffuse large B-cell lymphoma (DLBCL).

follicular lymphoma
burkitt's lymphoma
chemoimmunotherapy
large cell lymphoma
transformed lymphoma
  • 42 views
  • 31 Jan, 2022
  • 16 locations
A Promotion and Implementation Project of HIV Pre-Exposure Prophylaxis Among High Risk Population

This study aims to use a social media mini-application-enabled intervention to successfully promote the initiation and persistence of pre-exposure prophylaxis (PrEP) among at-risk men who have

Accepts healthy volunteers
  • 0 views
  • 10 Oct, 2021
  • 1 location
Cotrimoxazole Prophylaxis in Transurethral Resection or Greenlight Laser Vaporisation of the Prostate (CITrUS)

The optimal duration of antimicrobial prophylaxis (study medication Cotrimoxazole (Trimethoprim/Sulfamethoxazole)) in transurethral resection of the prostate and Greenlight Laser vaporisation of

  • 51 views
  • 14 May, 2022
  • 4 locations