Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 651 clinical trials
featured
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

This study will determine if a dexamethasone mouth rinse can reduce the risk of developing oral chronic graft-versus-host disease (cGVHD) in patients who have undergone a bone marrow (stem cell) transplant procedure. cGVHD is a common complication of stem cell transplantation, resulting from the donor cells attacking the transplant recipient's …

graft-versus-host disease
graft versus host disease
  • 38 views
  • 22 Dec, 2020
  • 1 location
featured
Adolescent BV - Impact of the vaginal microbiome on topical HIV pre-exposure prophylaxis (PrEP)

Through this study, we hope to learn how healthy bacteria and bacteria associated with a vaginal infection called bacterial vaginosis (BV) affect how PrEP works in women. BV is a common infection in young women that causes itching, odor, vaginal discharge, and inflammation. Women with BV may be at increased …

sexually transmitted infections
  • 47 views
  • 23 Nov, 2020
  • 1 location
featured
Haplo-identical Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using Peripheral Blood Stem Cells and Post-Transplant Cyclophosphamide for GVHD Prophylaxis

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MD) cause serious blood problems. Stem cell transplants using bone marrow or blood plus chemotherapy can help. Researchers want to see if using peripheral blood stem cells (PBSCs) rather than bone marrow cells works too. PBSCs are easier to collect and have …

myelodysplastic syndrome (mds)
aplastic anemia
anemia studies
myelodysplastic syndromes
anemia
  • 57 views
  • 22 Dec, 2020
  • 1 location
featured
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications

Background: Cord blood transplants can treat cancers and other diseases in children and adults. The U.S. Food and Drug Administration (FDA) requires cord blood to be collected and stored under certain safety standards. However, most available cord blood units were collected before the FDA set these standards. These units may …

myelodysplastic syndrome (mds)
aplastic anemia
anemia studies
myelodysplastic syndromes
anemia
  • 51 views
  • 22 Dec, 2020
  • 1 location
featured
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

Background: Cord blood is blood that is taken from the umbilical cord and placenta of healthy newborns after childbirth. The cord blood collected from a baby is called a cord blood unit. Cord blood units are stored frozen in public cord blood banks. About 10,000 cord blood transplants have been …

myelodysplastic syndrome (mds)
aplastic anemia
anemia studies
myelodysplastic syndromes
anemia
  • 79 views
  • 22 Dec, 2020
  • 1 location
Honey and Nigella Sativa in COVID-19 Prophylaxis

Honey and Nigella sativa has established antiviral, antibacterial, anti-inflammatory, and immunomodulatory roles. So it is planned to test for its prophylaxis

  • 1 views
  • 11 Jul, 2021
  • 1 location
PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V

illness if given as prophylaxis. Although vaccines are now available, there remains a need for other prophylactic agents until vaccine use becomes widespread globally and effectiveness and durability is

  • 0 views
  • 11 May, 2021
  • 1 location
Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis

This study is testing whether stratification of the patients according to biological risk factors for different treatment groups will improve the outcome of patients with clinically high diffuse large B-cell lymphoma (DLBCL).

b-cell lymphoma
follicular lymphoma
chemoimmunotherapy
burkitt's lymphoma
t-cell lymphoma
  • 32 views
  • 23 Jan, 2021
  • 18 locations
Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Have Sex With Men and Are at High Risk for HIV-1 Infection (MK-8591-024)

The main purpose of the study is to evaluate the efficacy and safety of oral Islatravir (ISL) once monthly (QM) as Preexposure Prophylaxis (PrEP) in cisgender men who have sex with men (MSM) and

  • 0 views
  • 19 Sep, 2021
  • 20 locations
Cotrimoxazole Prophylaxis in Transurethral Resection or Greenlight Laser Vaporisation of the Prostate

The optimal duration of antimicrobial prophylaxis (study medication Cotrimoxazole (Trimethoprim/Sulfamethoxazole)) in transurethral resection of the prostate and Greenlight Laser vaporisation of

  • 1 views
  • 05 Feb, 2021
  • 5 locations