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Found 30 clinical trials
Bromocriptine in the Treatment of Peripartum Cardiomyopathy (BRO-HF)

heart failure leading to disabling symptoms and decreased quality of life. Animal studies have suggested that prolactin is central to the development of PPCM. Prolactin has pro-inflammatory and

  • 37 views
  • 25 Feb, 2022
  • 1 location
Cabergoline for Lactation Inhibition After Second-Trimester Abortion or Loss

This research study investigates the use of a drug, cabergoline, given immediately after second-trimester abortion or perinatal loss to decrease breast engorgement. Cabergoline is a medication approved for the symptomatic treatment of pituitary adenomas that result in a hyperprolactinemic state (a brain tumor that results in milk leakage). The benefit …

  • 1 views
  • 01 Mar, 2021
  • 1 location
5HTP Regulation Of Asthma In Children

The purpose of this study is to learn more about if taking a supplement called 5-hydroxytryptophan (5HTP) can improve breathing and anxiety symptoms related to asthma. To help learn more subjects will either be assigned to a group that is taking the supplement (5HTP) or a group that is taking …

  • 0 views
  • 22 Mar, 2022
  • 1 location
The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement (CRC289A07)

Although placebo effects on depressive symptoms are well documented, the underlying mechanisms and moderating factors of expectation effects on mood and depression are poorly understood. Various studies show reduced reward processing in clinical and subclinical depression, presumably due to abnormalities in the dopamine (DA) system. Here, the investigators will test …

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
Growth Hormone Pretreatment in Poseidon Type IV Undergoing ICSI Using Minimal Induction Protocol: A Randomized Controlled Trial

This study is done aiming to Assess Efficiency of Growth hormone as an adjuvant in pretreatment of Poseidon type IV group " poor responders "undergoing ICSI using minimal induction protocol

Accepts healthy volunteers
  • 0 views
  • 29 Oct, 2021
  • 1 location
PRolaCT - Three Prolactinoma RCTs

This study aims to investigate if endoscopic trans-sphenoidal prolactinoma resection as a first line treatment, or as an equally valid second line treatment after a short (4-6 months) or long (>2 years) period of pretreatment with a dopamine agonist is superior to standard care for several outcome parameters. The main …

  • 0 views
  • 24 Jan, 2021
  • 3 locations
Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma

The aim of this study is to investigate whether inhibition of serum prolactin levels below normal range during cabergoline administration may reduce the recurrence rate after drug withdrawal in

prolactinoma
prolactin
drug withdrawal
cabergoline
  • 90 views
  • 27 Feb, 2022
  • 1 location
Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas

induce tumour shrinkage. At present, cabergoline is the dopamine agonist most widely used in the treatment of pituitary adenomas secreting prolactin. Aim is to study the effect of medical

prolactin
pituitary disorders
dopamine agonists
hypopituitarism
cabergoline
  • 65 views
  • 12 Sep, 2021
  • 3 locations
The Effect of Two Different General Anesthesia Regimes on Postoperative Sleep Quality

), regarding preoperative and long term postoperative sleep quality, sleep diaries regarding early postoperative sleep quality and biochemical markers (cortisol, prolactin and melatonin) regarding

anesthesia
major surgery
abdominal surgery
sleep disturbances
propofol
  • 76 views
  • 24 Mar, 2022
  • 1 location
Bromocriptine for Patients With Schizophrenia and Impaired Glucose Tolerance

change in IGT measured by HbA1c. Secondary metabolic outcome measures include body weight, fasting lipids, and prolactin. The specific aims are as follows: Specific aim 1: To establish the safety and

insulin
diabetes
prolactin
fasting
dopamine
  • 0 views
  • 06 Feb, 2022
  • 1 location