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Found 37 clinical trials
Bromocriptine in the Treatment of Peripartum Cardiomyopathy (BRO-HF)

heart failure leading to disabling symptoms and decreased quality of life. Animal studies have suggested that prolactin is central to the development of PPCM. Prolactin has pro-inflammatory and

  • 39 views
  • 25 Feb, 2022
  • 1 location
Psilocybin Versus Ketamine in Treatment-Resistant Depression (PSIKET_001)

will explore the role of plasmatic neurobiological biomarkers in depression (BDNF, prolactin, ACTH and oxytocin).

  • 11 views
  • 03 Jun, 2022
  • 1 location
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy (REBIRTH)

The study will enroll 200 women newly diagnosed with peripartum cardiomyopathy within 5 months postpartum in a randomized placebo controlled trial of bromocriptine therapy to evaluate its impact on myocardial recovery and clinical outcomes. Given that bromocriptine prevents breastfeeding, an additional 50 women with peripartum cardiomyopathy excluded from the trial …

  • 0 views
  • 28 Jun, 2022
  • 1 location
The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement (CRC289A07)

Although placebo effects on depressive symptoms are well documented, the underlying mechanisms and moderating factors of expectation effects on mood and depression are poorly understood. Various studies show reduced reward processing in clinical and subclinical depression, presumably due to abnormalities in the dopamine (DA) system. Here, the investigators will test …

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
Controlled Internal Convection in Low Flow Hemodialysis of Dialysate: Removal of Beta-2-microglobulin (CIMHBaDD)

Since 2013 daily home hemodialysis allows low volumes of convection. This study is a prospective cross-over trial testing the efficiency of internal convection on Beta2-microglobulin in daily home hemodialysis.

  • 0 views
  • 30 Jun, 2022
  • 1 location
5HTP Regulation Of Asthma In Children

The purpose of this study is to learn more about if taking a supplement called 5-hydroxytryptophan (5HTP) can improve breathing and anxiety symptoms related to asthma. To help learn more subjects will either be assigned to a group that is taking the supplement (5HTP) or a group that is taking …

  • 0 views
  • 22 Mar, 2022
  • 1 location
Growth Hormone Pretreatment in Poseidon Type IV Undergoing ICSI Using Minimal Induction Protocol: A Randomized Controlled Trial

This study is done aiming to Assess Efficiency of Growth hormone as an adjuvant in pretreatment of Poseidon type IV group " poor responders "undergoing ICSI using minimal induction protocol

Accepts healthy volunteers
  • 0 views
  • 29 Oct, 2021
  • 1 location
PRolaCT - Three Prolactinoma RCTs

This study aims to investigate if endoscopic trans-sphenoidal prolactinoma resection as a first line treatment, or as an equally valid second line treatment after a short (4-6 months) or long (>2 years) period of pretreatment with a dopamine agonist is superior to standard care for several outcome parameters. The main …

  • 0 views
  • 24 Jan, 2021
  • 3 locations
Prolactin Release Through Breast Stimulation in Non-lactating Women - Who Does Respond?

Prolactin is a multifunctional hormone which acts in different cell types rather than just modulating reproduction and lactation. One additional point is its action on glucose metabolism which

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma

The aim of this study is to investigate whether inhibition of serum prolactin levels below normal range during cabergoline administration may reduce the recurrence rate after drug withdrawal in

prolactin
drug withdrawal
prolactinoma
cabergoline
  • 90 views
  • 27 Feb, 2022
  • 1 location