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Found 45 clinical trials
Featured trial
New Approaches to Dementia Heterogeneity.

This study is looking for adults who have mild cognitive impairment, Alzheimer’s, or other forms of dementia. The study is also looking for people with normal cognition, as a comparison. The study is interested in the ways that brain function changes over time with the goal of improving the ability to diagnose …

amyotrophic lateral sclerosis
heart disease
mild cognitive impairment
dementia, frontotemporal
vascular dementia
  • 154 views
  • 25 May, 2021
  • 1 location
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy

This is a phase 1, multi-center, double-blind, placebo-controlled, multiple dose escalation study with NIO752 in progressive supranuclear palsy (PSP) participants.

gaze palsy
screening procedures
dopamine
coenzyme q
levodopa
  • 18 views
  • 10 Mar, 2022
  • 11 locations
Epidemiology and Pathophysiology of Parkinsonism in the Caribbeans

The primary aim of this study is to estimate the frequency and to characterize clinically atypical parkinsonism in the French West Indies and Guyana.

  • 0 views
  • 21 Jan, 2021
  • 2 locations
RT001 in Patients With Progressive Supranuclear Palsy (PSP) PROGRESSIVE SUPRANUCLEAR PALSY

This is a randomized, placebo-controlled trial of RT001 in patients with PSP.

  • 2 views
  • 26 Jan, 2022
  • 1 location
A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP)

This is a Phase 2a study to assess the safety and tolerability of TPN-101 patients with PSP.

  • 21 views
  • 13 May, 2022
  • 11 locations
Test-retest Study With [18F]PI-2620 in PSP-RS and NDC

The overall goal of this protocol is to evaluate the imaging characteristics of [18F]PI-2620 using positron emission tomography (PET) in patients with progressive supranuclear palsy

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 1 location
A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy

This study is designed to learn more about overall tau burden in the brain of patients with Progressive Supranuclear Palsy (PSP).

Accepts healthy volunteers
cognitive assessment
  • 124 views
  • 25 Jan, 2022
  • 1 location
Efficacy of RIVAstigmine on Motor, Cognitive and Behavioural Impairment in Progressive Supranuclear Palsy (RIVA-PSP)

Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease from the parkinsonian syndrome group. It represents 5 to 10% of all parkinsonian syndromes and affects 3,000 to 10,000

dopa
gaze palsy
mini-mental state examination
screening procedures
parkinsonism
  • 203 views
  • 09 Aug, 2022
  • 1 location
Community Outreach for Palliative Engagement -- Parkinson Disease (COPE-PD)

The purpose of this study is to learn more about the effectiveness of palliative care training for community physicians and telemedicine support services for patients and carepartners with Parkinson's disease and Lewy Body Dementia (LBD) or related conditions and their care partners. Palliative care is a treatment approach focused on …

parkinsonism
supranuclear palsy
depression
progressive supranuclear palsy
atrophy
  • 0 views
  • 10 May, 2022
  • 1 location
Trial of Parkinson's And Zoledronic Acid (TOPAZ)

This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will …

screening procedures
parkinsonism
supranuclear palsy
zoledronic acid 5mg/bag 100ml inj
progressive supranuclear palsy
  • 256 views
  • 12 May, 2022
  • 53 locations