Found 92 clinical trials
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low Hormone Receptor Positive Metastatic Breast Cancer
This study will evaluate the efficacy, safety and tolerability of trastuzumab deruxtecan compared with investigator's choice chemotherapy in human epidermal growth factor receptor (HER)2-low, hormone receptor (HR) positive breast cancer patients whose disease has progressed on endocrine therapy in the metastatic setting.
- 35 views
- 17 Jan, 2021
- 183 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For females only
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Combination Chemotherapy and Trastuzumab in Treating Women With Stage I Stage II or Stage III HER2-Positive Breast Cancer
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. …
- 33 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer
The goal of this research is to test the accuracy of PET/MRI imaging with 18F-fluorofuranylnorprogesterone (FFNP) for measuring progesterone receptor (PR) expression in patients with invasive
- 0 views
- 20 Dec, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
Cemiplimab in High Risk or Locally Advanced Hormone Receptor Positive HER2 Negative or Triple-Negative Breast Cancer
-N3), metastasis 0 (cM0), hormone receptor positive (HR+) (estrogen-receptor-positive (ER+) and/or progesterone-receptor-positive (PR+) human epidermal growth factor receptor 2 (HER2) negative or
- 0 views
- 24 Jan, 2021
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Combined Treatment of Cetuximab and Paclitaxel in Basal Like Breast Carcinoma
Basal like breast carcinoma is a Her2, estrogen receptor (ER) progesterone receptor (PR) negative breast cancer. It is notable for the high level of epidermal growth factor receptor (EGFR
- 2 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
A Pre-operative Window Study of Letrozole Plus PR Agonist (Megestrol Acetate) Versus Letrozole Alone in Post-menopausal Patients With ER-positive Breast Cancer
with a good clinical outcomes. This highlights a potential therapeutic opportunity. The PIONEER trial will investigate the effect of combining megestrol acetate (a progesterone receptor
- 3 views
- 17 Jan, 2021
- 1 location
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Unknown Phase
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Currently Recruiting
Role of 200 mg Versus 400mg Vaginal Progesterone in Prevention of Preterm Labor in Twin Gestation
The objective of the present study is to evaluate the effectiveness of two doses of vaginal progesterone(200mg versus400mg) and placebo in improving gestational age in twin pregnancy and its subsequent impact on perinatal outcome.
- 0 views
- 23 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer
RATIONALE: Diagnostic procedures, such as breast duct endoscopy, may improve the ability to detect breast cancer earlier and plan more effective treatment. PURPOSE: This phase II trial is studying how well breast duct endoscopy works in assessing cellular atypia (abnormal cells) in the breast ducts of women with a genetic …
- 0 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Obstetrics/Gynecology (Women’s Health)
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Currently Recruiting
Nipple Aspiration Ductal Lavage and Duct Endoscopy For Diagnostic Assessment in Women Undergoing Surgery for Breast Cancer
RATIONALE: Diagnostic procedures, such as nipple aspiration, ductal lavage, and breast duct endoscopy, may help doctors detect and assess breast cancer cells early and plan more effective treatment. PURPOSE: This phase II trial is studying how well nipple aspiration, ductal lavage, and duct endoscopy work in assessing cancer cells in …
- 0 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Currently Recruiting
Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients
Phase II, randomized, open-label, international, multicenter study to compare efficacy of standard chemotherapy vs. letrozole plus abemaciclib as neoadjuvant therapy in HR-positive/HER2-negative high/intermediate risk breast cancer patients
- 0 views
- 11 Oct, 2020
- 28 locations