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Found 12 clinical trials
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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

  • 248 views
  • 25 Mar, 2021
  • 1 location
featured
A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

  • 196 views
  • 25 Mar, 2021
  • 1 location
Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories

A randomized, multi-center, double-blind, three arm placebo-controlled study in male and non-pregnant, non-lactating female subjects aged 18 years to examine the safety and efficacy of two dosing regimens of hydrocortisone acetate 90 mg suppository administered with the Sephure applicator for the treatment of ulcerative colitis of the rectum.

  • 2 views
  • 25 Jun, 2021
  • 86 locations
Micronized Purified Flavonoid- Fraction (MPFF) in the Management of Radiation Proctitis

national and multi-center trial for medical therapy of chronic radiation proctitis inducing anorectal bleedings

  • 0 views
  • 26 Jan, 2021
  • 20 locations
A Trial Comparing Acute Toxicity in Patients With Gynecological Cancer Treated With VMAT

This is a randomized, controlled, open-label, prospective and longitudinal clinical trial. Rectal, intestinal and bladder EBRT-related toxicity will be assessed according to RTOG / EORTC scales at the first day of EBRT, during the 2nd, 3rd and 4th week of treatment, and 1, 3 and 6 months after the end …

cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
Efficacy Study of 4CMenB (Bexsero ) to Prevent Gonorrhoea Infection in Gay and Bisexual Men

This is a Phase 3, double-blinded, randomised placebo-controlled, multi-centred trial evaluating the efficacy of the four-component meningococcal B vaccine, 4CMenB (Bexsero), in the prevention of Neisseria gonorrhoeae infection.The targeted population is 18-40 years-old men (cis and trans), trans women and non-binary people who have sex with men (hereafter referred to …

  • 0 views
  • 22 Jul, 2021
  • 4 locations
A Study of Niclosamide Enemas in Subjects With Active Ulcerative Proctitis or Ulcerative Proctosigmoiditis

This will be a phase I/IIa, open-label, three-stage, single center study aimed at investigating the safety, the efficacy (clinical and endoscopic effects) and the pharmacokinetics of Niclosamide enema 150 mg/60 ml and 450 mg/60 ml in subjects with mild-to-moderate UP and UPS, defined as a Modified Mayo Score (MMS) 4 …

proctitis
endoscopy
hematochezia
enemas
  • 66 views
  • 18 Sep, 2021
  • 3 locations
Transverse Colostomy for Refractory Hemorrhagic Chronic Radiation Proctitis: a Prospective Cohort Study

Refractory rectal bleeding of chronic radiation proctitis (CRP) is still problematic and does not respond to medical treatments including reagents, endoscopic argon plasma coagulation (APC) or

blood transfusion
severe anemia
cancer
  • 0 views
  • 22 Jan, 2021
  • 2 locations
Post Implantation Syndrome and Administration on NSAIDs in Patients Undergoing EVAR for AAA

INTRODUCTION Post-implantation syndrome is the clinical and biochemical expression of an inflammatory response following endovascular repair of an aortic aneurysm. PIS is mainly a clinical condition associated with the implantation of an endograft and is diagnosed by the presence of fever accompanied by elevated WBC count above normal without any …

aortic aneurysm
interleukin-6
  • 7 views
  • 22 Jan, 2021
  • 1 location
Phenomics in Autoimmune and Inflammatory Diseases

The family of inflammatory/autoimmune systemic diseases (IAD) form a continuum from pure inflammatory diseases to pure autoimmune diseases, encompassing a large panel of inflammatory diseases with some autoimmune components, and vice versa. Cross phenotyping of patients with IAD should be heuristic and help revise the nosography and the understanding of …

autoimmune disease
systemic disease
ulceration
crohn's disease
uveitis
  • 328 views
  • 24 Jan, 2021
  • 3 locations