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Found 484 clinical trials
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ENSURE-AF

ENSURE-AF

  • 62 views
  • 23 Nov, 2020
  • 1 location
Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2)

ENCHANTED2 is an international, multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to assess different approaches to manage blood pressure (BP) in acute

  • 0 views
  • 25 Jan, 2021
  • 1 location
DIRECT-SAFE: A Randomized Controlled Trial of DIRECT Endovascular Clot Retrieval Versus Standard Bridging Thrombolysis With Endovascular Clot Retrieval

The study will be a multicentre, prospective, randomized, open label, blinded endpoint (PROBE) phase 3 trial (2 arm with 1:1 randomization) in ischemic stroke patients within 4.5 hours of stroke

arterial occlusion
clot
stroke
probe
  • 129 views
  • 23 Jan, 2021
  • 26 locations
Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion

prospective, randomised, open-label, blinded endpoint (PROBE) design.

plasminogen
alteplase
stroke
probe
stenosis
  • 0 views
  • 26 Jan, 2021
  • 4 locations
Trial of EXenatide in Acute Ischaemic Stroke

Phase 2, multi centre, prospective, randomised, open label, blinded end-point (PROBE) trial comparing Exenatide to Standard of Care. The sample size is 528 patients (264 in each arm).

  • 2 views
  • 23 Jan, 2021
  • 16 locations
Trial of Andexanet in ICH Patients Receiving an Oral FXa Inhibitor

Randomized, controlled clinical trial evaluating the efficacy and safety of andexanet versus usual standard of care in patients with intracranial hemorrhage anticoagulated with a direct oral anticoagulant

  • 19 views
  • 25 Jan, 2021
  • 134 locations
Outcome in Patients Treated With Intraarterial Thrombectomy - optiMAL Blood Pressure Control (OPTIMAL-BP)

Recent endovascular thrombectomy (EVT) trial have proven the effectiveness of intraarterial revascularization in patients with larger cerebral artery occlusion. The success rate of EVT is close to 80%, but only 50% of patients improve to independent functional outcome. Therefore, new treatment strategies are needed to reduce the futile revascularization. However, …

hypertension
intracerebral hemorrhage
cerebral infarction
arterial occlusion
stroke
  • 0 views
  • 25 Jan, 2021
  • 1 location
The BIOPRES Trial: Transrectal BIOpsies of the PRostate: End Versus Side-firing

The purpose of this study is to study the difference in prostate cancer between two prostate biopsy techniques, namely end-firing and side-firing. These differ in the angle at which the prostate is biopsied.

transrectal ultrasound
biopsy of prostate
  • 15 views
  • 07 Nov, 2020
  • 1 location
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

The purpose of this study is to evaluate the objective response rate (complete response [CR]+ partial response [PR]) of the selected dose regimen in participants with metastatic or surgically unresectable urothelial cancers that harbor specific FGFR genomic alterations.

adjuvant chemotherapy
measurable disease
erdafitinib
dose regimen
renal function
  • 40 views
  • 08 Jan, 2021
  • 147 locations
Pulmonary Vein Isolation With Versus Without Continued Antiarrhythmic Drugs in Persistent Atrial Fibrillation

In the POWDER 1 study, paroxysmal atrial fibrillation (AF) patients undergoing conventional contact force (CF)-guided PVI were investigated. Patients were randomized between continuing previously ineffective antiarrhythmic drug therapy (ADT) or stopping ADT at the end of the blanking period. This trial, showed an added value of ADT after ablation (in …

persistent atrial fibrillation
pulmonary vein isolation
paroxysmal atrial fibrillation
antiarrhythmic drug
  • 20 views
  • 28 Jul, 2019
  • 13 locations