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Found 761 clinical trials
Rapid Autopsy and Procurement of Cancer Tissue

Background Individuals with cancer of the lung, chest cavity, ovary, or bladder, as well as patients who have been treated with adoptive cell therapy unfortunately commonly succumb to their disease. Some agree to donate their bodies to cancer research that may help the medical community better understand these diseases. Studies …

cancer
stage iv non-small cell lung cancer
lung cancer
thymic carcinoma
ovarian cancer
  • 45 views
  • 05 Sep, 2023
  • 1 location
GIST: Assessment of Tumor Mutations and TKI Plasma Exposure

Gastrointestinal stromal tumors (GISTs) belong to the sarcoma group and are characterized by oncogenic mutations in the c-KIT, PDGFRA, BRAF and NF-1 genes that drive tumor growth. Since tyrosine kinase inhibitors (TKIs) have become available, the median survival of GIST patients increased from 9 months to over 5 years. Consequently, …

  • 1 views
  • 29 May, 2022
  • 1 location
Prognostic and Diagnostic Added Value of Medical Imaging in Gynecological Cancer (PRODIGYN) (PRODIGYN)

The goal of this observational study is to learn about the added diagnostic and prognostic value of advanced medical imaging procedures in cervical cancer, endometrial cancer and ovarian cancer. The main questions it aims to answer are: Does advanced medical imaging predict survival? Can advanced medical imaging improve radiotherapy target …

  • 0 views
  • 20 Aug, 2023
Double Lung Transplant REgistry Aimed for Lung-limited Malignancies (DREAM)

This is a prospective observational registration trial for patients who undergo lung transplantation for the treatment of the select groups of medically refractory cancers affecting the lungs alone without extrapulmonary nodal and distant metastasis.

  • 0 views
  • 08 Apr, 2023
Ovarium Cancer Detection by TEP's and ctDNA

Rationale: Cancer is primarily diagnosed by clinical presentation, imaging and pathological analysis of tissue biopsies, increasingly supported by molecular diagnostics tests. However, late diagnosis and misdiagnosis due to limitations of tissue biopsy acquisition remains a major problem. Therefore, a general blood test to pinpoint cancer early and adequately can be …

tumor markers
tumor cells
cancer of the ovary
  • 15 views
  • 12 Feb, 2022
  • 3 locations
Radiogenomics in Aerodigestive Tract Cancers

Aerodigestive tract cancers are common malignancies. These cancers were ranked to be top-ten cancer-related deaths in Taiwan. Although many new target therapies and immunotherapies have emerged, many of the treatment eventually fail. For example, a 30-40% failure rate has been reported for target therapy, and, even higher for immune checkpoint …

cancer
adenocarcinoma
positron emission tomography
fdg pet
esophagus cancer
  • 0 views
  • 07 Oct, 2022
  • 1 location
Liquid Biopsy for ctDNA in Peritoneal Lavage and Blood in Pancreatic Cancer (LIPAC)

Pancreatic cancer (PC) is a deadly disease and surgical resection of the tumor is the only hope of cure. Approximately 20-25% of the PC patients are candidates for intended curative resection, but despite microscopically radical resection the majority of patients will have recurrent disease within 2 years. This indicates that …

pdac
adenocarcinoma
cancer chemotherapy
KRAS
pancreatic resection
  • 0 views
  • 16 Jun, 2022
  • 1 location
Prognostic Value of Liver Cancer CTCs Isolated by a Novel Microfluidic Platform

This study aims to isolate CTCs in peripheral venous blood of liver cancer patients by inertial focusing principle-based microfluidic device, determine the relationship between the number of CTCs and patient prognosis and treatment response, detect mutation, copy number variation and mutation load in CTC cells and corresponding tissues using single-cell …

cancer
tumor cells
Accepts healthy volunteers
  • 0 views
  • 26 Mar, 2022
  • 1 location
Improved Assessment of Response in Metastatic Renal Cell Carcinoma Using Spectral-CT

The incidence of renal cancer in Denmark is approximately 900 new cases per year. Untreated, the 5-year survival rate for metastatic renal cancer (mRCC) is 2%. Development of angiogenesis inhibitors (AI) and check-point immunotherapy (CPI) has improved survival. Treatment efficacy is evaluated by CT scans, using RESIST 1.1 (Response Evaluation …

  • 4 views
  • 12 Feb, 2022
  • 1 location
Effect of Goserelin on the Protection of Ovarian Reserve During (Neo)Adjuvant Chemotherapy for Young Breast Cancer Patients: A Prospective Cohort Trial

The purpose of this study is to assess efficacy of gonadotropin-releasing hormone agonist (goserelin) on the preservation of ovarian reserve function in young breast cancer patients treated with (neo)adjuvant chemotherapy by serial measuring ovarian reserve markers (AMH and AFC.etc) before and after chemotherapy and long-term pregnancy outcomes. Meanwhile, to evaluate …

gonadotropin releasing hormone
breast cancer staging
adjuvant chemotherapy
immunostimulant
early-stage breast cancer
  • 0 views
  • 24 Oct, 2022
  • 1 location