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Found 104 clinical trials
Evaluation of the Severity of Right to Left Shunt in PFO Patients After Systemic Embolism

The aim of the project is to identify new risk indicators of PFO. The evaluation of the R-L shunt is based on the newly developed precise measurement technique. Moreover, this measurement of R-L shunt is feasible in a case when R-L shunt is present only intermittently. Multicentric study with 150 …

  • 0 views
  • 26 Jan, 2021
  • 6 locations
Oral Probiotics for the Treatment and Prevention of Vulvovaginal Infections in Pregnancy - Double-blind Randomized Placebo-controlled Study

During pregnancy, bacterial vaginosis (BV), abnormal vaginal flora (AVF) and vulvovaginal candidiasis (VVC) are associated with serious complications and discomfort. Yet, treatment options are limited. Lactobacilli administration was suggested to treat and prevent vaginal infections. However, this has not been examined in pregnant women, the information regarding oral treatment is …

  • 106 views
  • 26 Jan, 2021
  • 3 locations
Cyanoacrylate to Stop Bleeding After EMR for Large Polyps

Endoscopic resection of large non-pedunculated adenomas is most often performed using the 'lift-and-cut' endoscopic mucosal resection (EMR) technique. This endoscopic technique has a relatively low technical complexity and short-duration and is commonly considered a safe and reliable surgical option, nevertheless several adverse events can occur during or after this procedure. …

procedural bleeding
polypectomy
postoperative bleeding
adenoma
  • 0 views
  • 23 Jan, 2021
  • 1 location
A Home-based Intervention to Improve the Diet Quality of Preschoolers

U.S. children eat too little fruits and vegetables and whole grains, and too many energy dense foods, dietary behaviors associated with increased morbidity from cardiovascular diseases. Parents play a key role in shaping their child's diet and best practices suggest that parents should involve children in food preparation, offer, model …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Treatment of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant

Left ventricular thrombus is a common complication subsequent to ST-segment elevation myocardial infarction (STEMI) that related to increased embolic events. This study aims to assess the efficacy and safety outcomes of Rivaroxaban on the treatment of post-STEMI left ventricular thrombus.

clopidogrel
troponin
clot
warfarin
aspirin
  • 0 views
  • 24 Jan, 2021
  • 1 location
TrAstuzumab Cardiomyopathy Therapeutic Intervention With Carvedilol

Breast cancer patients undergoing trastuzumab-based HER2-directed therapy are at risk of heart function decline or heart failure symptoms, but it is unknown if, when, and for how long cardiovascular protective strategies, e.g. with a beta-blocker, could help. This study randomly assigns those taking curative-intent trastuzumab-based HER2-directed therapy to the beta-blocker …

her2/neu-positive breast cancer
mammogram
lapatinib
erbb2
trastuzumab
  • 1 views
  • 27 Jan, 2021
  • 3 locations
eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

This pilot randomized controlled trial seeks: (1) to determine the preliminary efficacy of our modernized collaborative care intervention for depression in improving the diabetes risk markers of hemoglobin A1c and insulin resistance and (2) to explore whether somatic depressive symptoms - i.e., hyperphagia (increased appetite/weight) and/or hypersomnia (increased sleep) - …

insulin resistance
glycosylated hemoglobin
depressive symptoms
diabetes
hemoglobin a1c
  • 0 views
  • 16 Feb, 2021
  • 1 location
Rosuvastatin Effect on Atherosclerotic Plaque Metabolism

Atherosclerotic plaque uptake of 18F-sodium fluoride (NaF) in positron emission tomography with computed tomography (PET-CT) was recently shown to correlate with clinical instability in patients with CV disease. We hypothesize that rosuvastatin reduces 18F-NaF plaque uptake. Our group will scan coronary, aortic and carotid arteries of high-risk CV subjects with …

  • 0 views
  • 26 Jan, 2021
  • 1 location
PITA-HF: Feasibility Safety and Tolerability

Heart failure affects over 25 million people worldwide and nearly 7 million adults in the United States alone. Nearly 25% of patients with heart failure have worsened disease burden from dyssynchronous ventricular contraction due to abnormal electrical impulse propagation. These patients may benefit from cardiac resynchronization therapy (CRT) where contraction …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Community Benefit of No-charge Calcium Score Screening Program

Current approaches in primary prevention for cardiovascular disease are based on probabilistic approaches to estimate risk, using many of the widely available cardiovascular risks scores, with

  • 0 views
  • 23 Jan, 2021
  • 1 location