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Found 106 clinical trials
Asian Diabetes Outcomes Prevention Trial (ADOPT)

using renin-angiotensin system (RAS) antagonists, beta-blockers and sodium glucose co-transporter-2 inhibitors (SGLT2i) for primary prevention of cardiovascular events in this high-risk DM population

type 2 diabetes mellitus
coronary revascularization
cardiovascular disease
primary prevention
heart failure
  • 148 views
  • 27 Feb, 2022
  • 1 location
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management

ischemic attack
angiography
carotid revascularization
stenosis
transient ischemic attack
  • 1155 views
  • 19 Jun, 2022
  • 131 locations
Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK)

aspirin as primary prevention in people with CKD who have not had a CVD to prevent the first event, to assess whether the potential benefits exceed the risks. Eligible patients will be recruited

clot
chronic disease
cardiovascular disease
primary prevention
glomerular filtration rate
  • 0 views
  • 25 Mar, 2022
  • 1 location
Effects of Carvedilol on Cardiotoxicity in Cancer Patients Submitted to Anthracycline Therapy

evidence is still needed. This is a multi-center, double-blind, randomized, placebo-controlled study that aims to establish the efficacy of carvedilol for the primary prevention of left ventricular

treatment regimen
primary cancer
anthracyclines
  • 0 views
  • 08 Oct, 2021
  • 1 location
Aspirin in Colorectal Cancer Liver Metastases (ASAC)

disease free survival in patients treated with resection for colorectal cancer liver metastases (CRCLM). Several studies have shown beneficial effect of ASA on primary prevention of CRC and the

cancer
liver metastasis
aspirin
primary tumor
metastasis
  • 205 views
  • 29 Apr, 2022
  • 15 locations
Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial) (CARTIER)

endpoint is to determine whether this primary prevention englobing cardiovascular monitoring plus intensive multidisciplinary management is superior to the current clinical practice in reducing all cause

cancer
early detection
primary cancer
breast cancer
lymphoma
  • 7 views
  • 17 Jun, 2022
  • 1 location
Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction.

Contemporary heart failure (HF) guidelines recommend insertion of a primary prevention implantable defibrillator (ICD) in patients with left ventricular ejection fraction less than 35% (LVEF &lt

systolic dysfunction
angiotensin
ace inhibitor
left ventricular systolic dysfunction
sudden cardiac death
  • 84 views
  • 26 Jan, 2021
  • 20 locations
Efficiency of Prevention Program Dedicated to Addictive Behaviors (PREVENTURE) of Vulnerable Teenagers

effective primary prevention strategies for dealing with addictive behavior. Many prevention programs target age range in school settings, to delay or reduce use of psychoactive substances. A meta

substance use
anxiety
  • 0 views
  • 15 Dec, 2021
  • 5 locations
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD (WARRIOR)

The Ischemia-IMT (Ischemia-Intensive Medical Treatment Reduces Events in Women with Non-Obstructive CAD), subtitle: Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR) trial is a multicenter, prospective, randomized, blinded outcome evaluation (PROBE design) evaluating intensive statin/ACE-I (or ARB)/aspirin treatment (IMT) vs. usual care (UC) in 4,422 symptomatic women patients …

rosuvastatin
coronary ct
angina pectoris
aspirin
chest pain
  • 557 views
  • 26 Feb, 2022
  • 84 locations
Using Big Data to Conduct Innovative Cardiovascular Clinical Trials

Traditional randomized clinical trials (RCTs) have provided extremely valuable information on medical therapies and procedures that have changed the way heart diseases are treated. However, despite these contributions, traditional RCTs are costly, the findings may not be applicable to patients unlike those in the study, and the use of trial …

statin
heart disease
cholesterol measurement
myocardial infarction
cholesterol level
  • 3 views
  • 26 Feb, 2022
  • 1 location