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Found 102 clinical trials
Rare CNS Tumors Outcomes &Risk

Background Primary tumors of the brain and spine are those that start in the brain or spine. These tumors are rare, accounting for <2% of all cancers diagnosed in the United States. Some of these tumors occur in less than 2,000 people per year. Researchers want to study a large …

primitive neuroectodermal tumor
atypical teratoid/rhabdoid tumor
anaplastic oligodendroglioma
  • 25 Jan, 2021
  • 1 location
The Genetics and Vascular Health Check Study (GENVASC) Aims to Help Determine Whether Gathering Genetic Information Can Improve the Prediction of Risk of Coronary Artery Disease (CAD)

The Genetics and Vascular Health Check study (GENVASC) is a large study run in conjunction with Clinical Commissioning Groups and Primary Care practices across Leicester, Leicestershire and Northamptonshire. The purpose of GENVASC is to help determine whether gathering genetic information can improve the prediction of risk of Coronary Artery Disease …

coronary disease
  • 24 Jan, 2021
  • 1 location
Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management

Myocarditis is a complex inflammatory disease, usually occurring secondary to viral infections, autoimmune processes or toxic agents. Clinical presentations are multiple, including chest-pain, heart failure and a broad spectrum of arrhythmias. In turn, outcome is largely unpredictable, ranging from mild self-limiting disease, to chronic stage and progressive evolution towards dilated …

heart failure
endomyocardial biopsy
ventricular arrhythmia
heart disease
inflammatory disorder
  • 24 Jan, 2021
  • 1 location
Thromboembolic and Bleeding Risk Stratification in Patients With Non-valvular Atrial Fibrillation

The aim of the present prospective study is to further develop and validate a composite risk score predicting both ischemic and bleeding risk, based on epidemiologic, clinical, biological, and/or morphologic complementary data. First, the investigators will assess the predictive performance of current clinical risk scores. Second, the investigators will assess …

  • 24 Jan, 2021
  • 6 locations
Benefits of ICD for the Primary Prevention in Patients With Valvular Cardiomyopathy

prevalent in Asia than in Western countries, and the frequency of valve disease is higher in Asia. The effect of an implantable cardioverter defibrillator (ICD) in the primary prevention of sudden cardiac

heart failure
implantable cardioverter-defibrillators
heart disease
  • 24 Jan, 2021
  • 12 locations
Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection

. Primary prevention and secondary education and screening for these pathologies are still insufficient. A better understanding of the pathophysiology of these placental vascular pathologies is necessary

premature birth
toxemia of pregnancy
fetal growth retardation
  • 24 Jan, 2021
  • 1 location
International Electrical Storm Registry

patient to experience an ES. The incidence of ES is debated in different studies and ranges from 10 to 60% in patients with ICD for secondary prevention and from 4 to 7% in patients with ICD for primary

cardiac death
sustained ventricular tachycardia
primary prevention
ventricular arrhythmia
  • 22 Jan, 2021
  • 1 location
PRogetto Salute Parma

internationally validated scientific methods. Secondary objectives: To evaluate the use of local smoking cessation clinics and their effects in terms of smoking cessation (primary prevention

lung carcinoma
lung cancer
ct scan
  • 24 Jan, 2021
  • 1 location
Prediction of ARrhythmic Events With Positron Emission Tomography II

Sudden cardiac death continues to be a major contributor to mortality in patients with ischemic cardiomyopathy. While implantable defibrillators can prevent death from ventricular arrhythmias, our current approach to identify patients at highest risk primarily rests on demonstrating a reduction in left ventricular ejection fraction less than 35%. The purpose …

brain natriuretic peptide
myocardial infarction
enzyme inhibitors
primary prevention
medical therapy
  • 23 Jan, 2021
  • 1 location
PLASMA Mexico (PLASMA Mexico)

Collect data on Mexican patients diagnosed with Heart Failure with reduced ejection fraction, their treatments, and their progress in a real-world environment. Additional objectives will be analyzed, such as mortality, the use of resources associated with the follow-up of this group of patients and the barriers, if any, to receiving …

heart failure
ejection fraction
  • 13 Feb, 2021
  • 4 locations