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Found 71 clinical trials
Oscillatory Contributions to Working Memory and Attention

hypothesis that the function of context binding contributes to delay-period activity of the posterior parietal cortex (PPC).

Accepts healthy volunteers
  • 07 Oct, 2022
  • 1 location
Brain State-dependent Stimulation to Improve Movement (BrainSTIM)

Repetitive transcranial magnetic stimulation (rTMS) is a powerful tool to non-invasively modulate brain circuits, brain plasticity, and behavior. This proposal will test the hypothesis that controlling behavioral state during focal multi-day rTMS of a brain region involved in grasping movements will enhance the functional specificity of the neuromodulation action among …

Accepts healthy volunteers
  • 06 Apr, 2022
  • 1 location
Effect of Preoperative Incentive Spirometer on Postoperative Pulmonary Complications Following Lung Resection

The objective of this study is to demonstrate that inspiratory muscle training with daily use of an incentive spirometer for at least 14 days prior to lung surgery will reduce the risk of post-operative pulmonary complications.

Accepts healthy volunteers
  • 04 Jun, 2022
  • 1 location
Effectiveness of Specialised Paediatric Palliative Care (SPhAERA)

This study evaluates the effectiveness of an existing Specialised Paediatric Palliative Care programme and reports on its potential to improve patient-, family-, health professionals-, and healthcare-related outcomes. Data will be compared between an intervention and a comparison group.

  • 24 Feb, 2022
  • 1 location
In-depth Investigation of Brain Network Interactions (BNI)

Brain stimulation is a means to potentially remediate symptoms in a range of neurological and psychiatric diseases, however, precise targeting of stimulation is necessary to ensure efficacy. The proposed project will use recent advances in functional magnetic resonance imaging to delineate distributed brain networks within individuals, and use these network …

  • 04 Oct, 2022
  • 1 location
Study Of Intraperitoneal EGEN-001 Administered In Combination With Pegylated Liposomal-Doxorubicin In Patients With Recurrent Or Persistent Epithelial Ovarian Fallopian Tube Or Peritoneal Cancer

Pegylated liposomal doxorubicin (PLD; e.g., Doxil®, Lipodox™) will be administered intravenously on Day 1 and EGEN-001 will be administered intraperitoneally on Day 1, 8, 15, and 22 of a 28-day cycle to determine: - The maximum tolerated dose (MTD) and dose limiting toxicities (DLTs) of EGEN-001 when administered in combination …

intraperitoneal chemotherapy
peritoneal cancer
  • 08 Nov, 2020
  • 1 location
Protective Ventilation With High Versus Low PEEP During One-lung Ventilation for Thoracic Surgery

> Anesthesiologists inconsistently use PEEP and recruitment maneuvers (RM) in the hope that this may improve oxygenation and protect against PPC. Up to now, it is not known whether high levels of PEEP combined with

  • 23 Mar, 2022
  • 58 locations
A Phase 1/2a/3 Evaluation of the Safety and Efficacy of Adding AL3818 (Anlotinib, INN: Catequentinib), a Dual Receptor Tyrosine Kinase Inhibitor, to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818)

This trial is a Phase 1b/2a/3 trial designed to evaluate the safety and efficacy of adding oral AL3818 (Anlotinib, INN: Catequentinib), a Dual Receptor Tyrosine Kinase Inhibitor, to standard platinum-based chemotherapy concurrently in Subjects with Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma.

serum pregnancy test
international normalized ratio
undifferentiated carcinoma
  • 11 Oct, 2022
  • 23 locations
Sensori-motor and Perceptual Functions of the PPC. (PPCfonctions)

To produce hand's movement directed towards a target, the investigator must combine several sensory information, such as vision or proprioception. The posterior parietal cortex (PPC) is a region

Accepts healthy volunteers
  • 26 Feb, 2022
  • 1 location
A Phase II Trial Evaluating Feasibility and Quality of Life of Second Look Laparoscopy With HIPEC in Patients With Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma (HIPEC)

The purpose of this research study is to see if it is feasible to receive heated chemotherapy or heated intraperitoneal chemotherapy (HIPEC) inserted directly into the abdomen at the time of a Second Look Reassessment Surgery and to monitor any effects good or bad that this has on participants' health.

tumor markers
absolute neutrophil count
cytoreductive surgery
  • 21 Oct, 2022
  • 1 location