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Found 64 clinical trials
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A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

glaucoma
intraocular pressure
  • 17 views
  • 10 Mar, 2022
  • 1 location
The Effectiveness of YAG Iridotomy in Preventing Peripheral Anterior Synechia After CLASS in Primary Open Angle Glaucoma

To investigate the effectiveness of YAG laser iridotomy in preventing peripheral anterior synechia after CO2 Laser-Assisted Sclerectomy Surgery and the long-term effect of reducing intraocular pressure

hypotensive
hypotensive agents
brimonidine tartrate ophthalmic solution
intraocular pressure
primary open angle glaucoma
  • 0 views
  • 14 Jun, 2021
  • 1 location
Comparation of CLASS Combined With Phacoemulsification and CLASS Alone in the Treatment of Primary Open Angle Glaucoma

primary open-angle glaucoma

hypotensive
phacoemulsification
cataract
hypotensive agents
brimonidine tartrate ophthalmic solution
  • 0 views
  • 20 Jun, 2021
  • 1 location
The Effect of Dronabinol on Ocular Hemodynamics in Patients With Primary Open Angle Glaucoma

investigate whether single administration of dronabinol alters optic nerve head (ONH) blood flow in patients with open angle glaucoma. In addition, other parameters for ocular blood flow will be measured, in

  • 11 views
  • 12 Sep, 2021
  • 1 location
Evaluating Home Testing Devices for the Management of Glaucoma

With the advancement in technology we have the opportunity of performing the glaucoma testing at home to monitor the disease. The purpose of this study is evaluating the feasibility and patient acceptance of home testing with head mounted perimetry; detection of progression with head mounted perimetry vs office based perimetry; …

astigmatism
refractive error
optical coherence tomography
  • 3 views
  • 12 May, 2022
  • 1 location
Adaptive Optics Retinal Imaging

The objective of the study is to collect and assess adaptive optics (AO) retinal images from human subjects in support of projects to demonstrate, advance, and enhance clinical use of AO technology.

Accepts healthy volunteers
  • 0 views
  • 28 May, 2022
  • 1 location
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis

This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with symptomatic irreversible pulpitis.

Accepts healthy volunteers
  • 29 views
  • 28 Feb, 2022
  • 1 location
A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

This is a randomized, Investigator-masked, multi-center, parallel group, therapeutic equivalence study with clinical endpoint.

hypotensive
ocular hypotensive
glaucoma
brinzolamide ophthalmic suspension
brinzolamide
  • 8 views
  • 09 Jul, 2022
  • 29 locations
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.

Evaluate the safety and effectiveness of iSTAR Medical's MINIject implant for lowering intraocular pressure (IOP) in subjects with primary open-angle glaucoma.

filtration surgery
glaucoma
drainage
glaucoma surgery
medical therapy
  • 0 views
  • 04 Sep, 2021
  • 1 location
MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Denali)

-angle glaucoma. Subjects will be randomized in a 1:1 ratio to NCX 470 0.1% or to latanoprost 0.005% to be administered to both eyes once daily in the evening for up to 12 months.

corrected visual acuity
intraocular pressure
glaucoma
hypertension
ophthalmic solution
  • 1 views
  • 10 May, 2022
  • 1 location