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Found 242 clinical trials
Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and Youth

chronic anger, sadness, or irritability, as well as hyperarousal (such as insomnia, distractibility, hyperactivity) and extreme responses to frustration (such as frequent, severe temper tantrums

psychiatric disorder
depressive disorder
brain imaging
neurological examination
  • 23 Oct, 2022
  • 1 location
Genetic Characterization of Movement Disorders and Dementias

Background There are two basic types of movement disorders. Some cause excessive movement, some cause slowness or lack of movement. Some of these are caused by mutations in genes. On the other hand, dementia is a condition of declining mental abilities, especially memory. Dementia can occur at any age but …

heart disease
Accepts healthy volunteers
cognitive impairment
  • 28 Oct, 2022
  • 1 location
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to …

Accepts healthy volunteers
  • 04 Mar, 2022
  • 43 locations
The Norwegian Cerebral Venous Thrombosis Study (NoCVT)

The NoCVT study will investigate CVT (2010-2019) in a large Norwegian population (> 3 millions) using several approaches combining existing health registries, clinical databases and new prospectively collected clinical data to explore epidemiology, risk factors, diagnostics, treatment, and the long-term prognosis of CVT.

  • 13 Jun, 2022
  • 1 location
Patient's Whole Process Follow-up Management(HOPE-1) (HOPE-1)

Our project is going to explore whether management and follow-up of locally advanced/metastatic patients using the patient process management platform can prolong patient survival and improve patient quality of life.

  • 07 Oct, 2022
  • 1 location
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research. We make it easy for patients to contribute to research for medical conditions that matter most to them, regardless of their location or ability to travel.

Accepts healthy volunteers
  • 26 Jan, 2022
  • 1 location
Neurodegenerative Diseases Registry (NDD Registry)

With the increase in life expectancy of our population due to advancement of medical diagnosis and treatments, the incidence of age dependent neurodegenerative diseases increased, including Alzheimer's disease (AD), parkinsonian syndromes (PS), small vessel disease (SVD) and motor neuron disease (MND). In spite of the progress of knowing the pathogenesis …

alzheimer's disease
supranuclear palsy
progressive supranuclear palsy
Accepts healthy volunteers
  • 26 Jan, 2022
  • 1 location
The Multi-Ethnic Lifestyle Study (MELS)

The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire. The study will adopt a convenient and purposive sampling recruitment strategy across a variety of settings within Leicestershire to facilitate recruitment of a wide range of participants.

Accepts healthy volunteers
  • 26 Feb, 2022
  • 1 location
Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis

This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which we believe is detrimental to MS. We will examine clinical data (MRI, lab results, medical history, labs, and sleep studies) of Dr. Sloane's MS patients. …

  • 26 Jan, 2021
The Impact of Insomnia on Pain in HIV (HIPPI)

The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to

psychiatric disorder
hiv diagnosis
HIV Vaccine
sleep disorder
Accepts healthy volunteers
  • 06 Jun, 2022
  • 1 location