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Found 877 clinical trials
Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes

This study examines at-home monitoring of patient-generated phsyiologic health data and patient-reported outcomes. Patient-generated health data using at-home monitoring devices and smart device applications are used more and more to measure value and quality in cancer care. This trial may show whether at-home monitoring programs can improve the care of …

cancer care
primary cancer
cancer treatment
cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
Detection of MSI in Circulating Tumor DNA of Colorectal Carcinoma Patients

This pilot trial studies how well serial liquid biopsies work in detecting microsatellite instability in participants with stage IV colorectal cancer. Serial liquid biopsies may help doctors learn better methods to track cancer in the bloodstream and how to use these to improve cancer treatments.

  • 0 views
  • 11 Apr, 2021
  • 4 locations
Hypofractionated Palliative Radiotherapy (39Gy in 13 Fractions) in Patients With Advanced Non-operable Rectal Cancer

Many patients with rectal cancer were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases. In this scenario only comfort measures or different palliative radiotherapy regimens are applied, from single doses to treatments lasting several weeks. The aim of this prospective study is to describe the …

metastasis
  • 0 views
  • 24 Jan, 2021
  • 1 location
Radiomic Signature as Predictive Marker of Response to Chemoradiation and Durvalumab in Stage III NSCLC.

The introduction of maintenance immunotherapy with the anti PD-L1 inhibitor durvalumab opened a new therapeutic window for stage III NSCLC patients who achieve at least stable disease after chemo-radiation, as shown by the randomized phase 3 PACIFIC study. However, still half of the patients do progress at 12 months (up …

durvalumab
cancer
stage iii non-small cell lung cancer
lung cancer
lung carcinoma
  • 0 views
  • 25 Jan, 2021
Measuring the Impact of Low Radiotherapy Doses on Bone Marrow

Bone marrow is one of the organs at risk of complications during irradiation due to its radiosensitivity. Hematopoietic toxicity remains one of the main toxicities during irradiation of pelvic lymph node areas, especially when concomitant chemotherapy is used, volume of bone marrow irradiated is large and dose to the bone …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Sentinel Node Extended in Squamous Cell Vulvar Cancer

The aim of this study is to investigate the feasibility of sentinel node biopsy in patients with squamous cell vulvar cancer, currently not regarded suitable for the sentinel node technique, i.e. patients with tumors 4cm, multifocal tumors or locally recurrent disease. A positive result of this pilot study might constitute …

lymphadenectomy
primary tumor
sentinel node
sentinel lymph node biopsy
  • 0 views
  • 23 Jan, 2021
  • 4 locations
Evaluation of Clinical Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

The aim of this study is the characterization from epidemiological, radiomics and molecular point of view of lung metastasis of patients at beginning affected by pancreatic adenocarcinoma (PDAC), which after the resection of primitive tumor have met with initial recurrence of the disease exclusively at the lung level.

pdac
metastasis
  • 0 views
  • 24 Jan, 2021
  • 4 locations
Transoral Robotic Surgery for rECurrent Tumours of the Upper Aerodigestive Tract

transoral Robotic surgery for rECurrent tumours of the Upper aerodigestive Tract

  • 0 views
  • 28 Jan, 2021
  • 2 locations
Evaluation of Effectiveness of CyberKnife Stereotactic Radiosurgery for Spinal Tumors

This study aims to explore the reliability of the combination of functional magnetic resonance imaging and radiomics for evaluation of the therapeutic efficacy of CyberKnife stereotactic radiosurgery for spinal tumors. Accurate imaging assessment can help clinicians plan personalized therapeutic schedules for patients with spinal tumors .

  • 0 views
  • 23 Jan, 2021
A Study to Assess Disease Burden in Terms of Health-related Quality of Life and Direct Healthcare Costs in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Autologous Stem Cell Transplant (ASCT) in Spain

Those patients with newly diagnosed Multiple Myeloma (MM) who are not candidates for Autologous Stem Cell Transplant (ASCT) and who meet the screening criteria described in this protocol can participate. The participating patients must sign an informed consent, which the investigator who will collect the study variables in an electronic …

  • 50 views
  • 04 Feb, 2021
  • 85 locations