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Found 847 clinical trials
SentoClone Compared to Reference Treatment in Advanced Malignant Melanoma

The purpose of this study is to elucidate whether SentoClone® gives improved treatment responses in patients with advanced malignant melanoma in comparison to established reference treatment(s).

temozolomide
measurable disease
dacarbazine
metastasis
  • 14 views
  • 08 Nov, 2020
  • 5 locations
Microwave Ablation in Combination With Camrelizumab Versus Camrelizumab in Metastatic Non-small-cell Lung Cancer

Patients were randomized to microwave ablation plus camrelizumab group or camrelizumab group.

  • 0 views
  • 26 Jan, 2021
  • 13 locations
A Study on the Efficacy and Safety of Bevacizumab in Untreated Patients With Locally Advanced Cervical Cancer

To verify the clinical efficacy and safety of bevacizumab in treating local advanced cervical cancer, present study was designed to investigate the clinical results of bevacizumab combined with concurrent chemoradiotherapy (CCRT) in local advanced cervical cancer

  • 1 views
  • 25 Jan, 2021
  • 1 location
Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.

Although many intratympanic agents have been attempted, N-Acetylcysteine (NAC) appears to be the most promising and is a powerful, commonly used anti-oxidant. The goal of this prospective phase 2 randomized controlled trial is to determine the optimal dosage and effectiveness of intratympanic NAC injection in reducing hearing loss in head …

  • 3 views
  • 24 Jan, 2021
  • 1 location
Tislelizumab Neo-adjuvant Treatment for Resectable RHCC

This single-arm phase II clinical trial aimed to explore the efficacy and safety of Tislelizumab as neoadjuvant treatment for resectable RHCC patients

  • 0 views
  • 28 Jan, 2021
  • 1 location
Active Surveillance of Papillary Thyroid Microcarcinoma

The purpose of this study is to better understand the outcomes of active surveillance (observation) instead of immediate surgery, which is the current standard of care for papillary thyroid microcarcinoma (PTMC). Patients with a 1.5 cm or smaller thyroid nodule(s) with papillary thyroid carcinoma will be eligible for the study.

  • 4 views
  • 26 Jan, 2021
  • 1 location
Chemotherapy Followed by Irreversible Electroporation in Patients With Unresectable Locally Advanced Pancreatic Cancer

This study is a single-arm clinical trial of irreversible electroporation (IRE) for the treatment of unresectable locally advanced pancreatic cancer (LAPC). The aim of the study is to evaluate the efficacy of IRE in this patient group. A statistical analysis of patient survival will be performed, comparing study participants to …

cancer
adenocarcinoma
carcinoma
solid tumors
  • 4 views
  • 23 Jan, 2021
  • 1 location
Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy

The purpose of this study is to determine if giving Cialis for 5 days prior to surgery, on the day of surgery along with the influenza vaccine and Cialis 10 days after surgery will have an affect at the cell level for decreasing the chances of the spread of disease …

vasectomy
platelet count
cervical cap
  • 27 views
  • 26 Jan, 2021
  • 1 location
Adenoid Cystic Carcinoma Erbitux and Particle Therapy

The ACCEPT (A(denoid) c(ystic) c(arcinoma), E(rbitux, and) p(article) t(herapy))-trial is a prospective, monocentric phase I/II feasibility trial evaluating toxicity and efficacy in the combined treatment of intensity-modulated radiation therapy (IMRT) and carbon ion (C12) boost with the epidermal growth factor receptor (EGFR) antibody cetuximab. The primary objective of the study …

  • 68 views
  • 08 Nov, 2020
Adjuvant Nivolumab Treatment in Stage II (IIA IIB IIC) High-risk Melanoma

Stage II patients with primary surgical treatment of cuMM are often at risk for recurrence of their disease. This risk may be reduced by adjuvant systemic treatment. Due to toxicities of adjuvant therapies the aim is to identify patients at high risk for relapse and to administer adjuvant treatment only …

  • 0 views
  • 23 Feb, 2021
  • 22 locations