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Found 859 clinical trials
REJOIN Trial for Older Breast Cancer Survivors

) associated with Aromatase Inhibitors (AI) in older breast cancer survivors. Survivors will be recruited from local cancer clinics prior to the completion of primary cancer treatment, as arthralgia can occur

cancer
breast cancer
aromatase inhibitor
  • 0 views
  • 04 Mar, 2021
  • 1 location
OPHTHALMOLOGIC EVALUATION OF RADIATION-RELATED OPTIC NEUROPATHY FOLLOWING IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY (IMRT) FOR NASOPHARYNGEAL CARC NOMA

Primary treatment in nasopharynx cancers is radiotherapy (RT) or chemoradiotherapy (CRT) depending on the stage of the tumor. According to the guidelines, the dose of radiotherapy for primary

  • 0 views
  • 28 Jan, 2021
  • 1 location
Impact of Selective Radiation Dose Escalation and Tumour Hypoxia Status on Locoregional Tumour Control After Radiochemotherapy of HNT

escalated Intensity Modulated Radiotherapy (IMRT) selectively applied to the macroscopic primary tumor and involved neck nodes - which both in 80% - are hypoxic improves loco-regional control by at least 15

  • 9 views
  • 21 Jan, 2021
  • 2 locations
Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer

within tumor tissues), is distributed within the bloodstream in some extent, when combined with Gemcitabine it can inhibit primary-tumor progression and dissemination. Our results tend to demonstrate

ductal adenocarcinoma
antineoplastic
pancreatic ductal adenocarcinoma
folfirinox
pdac
  • 27 views
  • 24 Jan, 2021
  • 10 locations
The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

The aim of this trial is to evaluate the value of palliative primary tumor resection in colon cancer patients with initially unresectable metastases and a positive response to induction

adenocarcinoma of colon
systemic chemotherapy
metastasis
adenocarcinoma
cancer
  • 0 views
  • 24 Jan, 2021
  • 1 location
A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer

carboplatin is manageable and induces reasonable response rates in patients with advanced recurrent, platinum-sensitive ovarian cancer. Biomarkers will be collected from both primary tumors and

cancer antigen 125
fallopian tube
carcinoma
carboplatin
ovarian epithelial cancer
  • 10 views
  • 07 Nov, 2020
  • 1 location
Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum

To study the effect of the timing of surgery on outcome of patients with nonmetastatic osteosarcoma of pelvis and sacrum.

  • 5 views
  • 22 Jan, 2021
  • 1 location
Hyperpolarized 13C Pyruvate MRI for Treatment Response Assessment in Patients With Locally Advanced or Metastatic Pancreatic Cancer

This phase II trial investigates whether magnetic resonance imaging (MRI) using hyperpolarized carbon-13 (13C) pyruvate can be useful for evaluating early treatment response in patients with pancreatic cancer that has spread to nearby tissue or lymph nodes (locally advanced) or spread to other places in the body (metastatic). Hyperpolarized 13C …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Survival Benefit of Elective Neck Dissection in T1 2N0M0 Oral Squamous Cell Carcinoma

Controversy over surgical treatment of clinically negative neck in early stage oral squamous cell carcinoma revolves around the uncertainty of its impact on patient prognosis. The efficacy of elective neck dissection on prognosis in T1, 2 N0M0 patients continues to be the subject of clinical debate. Currently the clinically negative …

  • 4 views
  • 21 Jan, 2021
  • 2 locations
SentoClone Compared to Reference Treatment in Advanced Malignant Melanoma

The purpose of this study is to elucidate whether SentoClone® gives improved treatment responses in patients with advanced malignant melanoma in comparison to established reference treatment(s).

metastasis
measurable disease
temozolomide
dacarbazine
  • 14 views
  • 08 Nov, 2020
  • 5 locations