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Found 929 clinical trials
Featured trial
Metastatic Colorectal Cancer with wild-type KRAS tumors.

Metastatic Colorectal Cancer with wild-type KRAS tumors.

  • 266 views
  • 25 Mar, 2021
  • 1 location
Standard Versus Super-extended Lymphadenectomy After Neo-adjuvant Chemotherapy for Gastric Cancer (Neo-D2plus)

In this study the patients with histological evidence of adenocarcinoma of the stomach will be screened and, if eligible, submitted to neo-adjuvant chemotherapy (NAC). After conclusions of NAC and obtaining informed consent, they will be registered and randomized to receive surgical D2 vs. D2plus lymphadenectomy.

  • 0 views
  • 09 Feb, 2022
  • 1 location
Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer

The purpose of this study is to compare effectiveness of short-term radiotherapy with neoadjuvant chemotherapy(TNT group) with preoperative long-term chemoradiotherapy(CRT group) in locally advanced rectal cancer. The hypothesis is 3-year disease-free survival in TNT group was non-inferior to that in CRT group.

adenocarcinoma of rectum
adenocarcinoma
chemoradiotherapy
pelvic mri
  • 0 views
  • 21 Jul, 2021
  • 1 location
Primary Tumor Resection With EGFR TKI for Stage IV NSCLC

Our project is going to enroll patients with stage IV NSCLC with EGFR mutation and evaluate whether primary tumor resection after receiving the afatinib can prolong survival. This project is

  • 0 views
  • 09 Apr, 2022
  • 2 locations
Neo-adjuvant Chemotherapy Combined With Stereotactic Body Radiotherapy to the Primary Tumour +/- Durvalumab, +/- Oleclumab in Luminal B Breast Cancer: (Neo-CheckRay)

combination of weekly paclitaxel followed by dose-dense doxorubicin-cyclophosphamide (ddAC) and pre-operative radiation therapy (boost dose) on the primary tumour arm 1 with the addition of the anti

  • 0 views
  • 11 Mar, 2022
  • 5 locations
MRI Screening of Second Primary Cancer Occurring Within Radiation Fields After Treatment by External Beam Radiation Therapy for Hereditary Retinoblastoma (DepiSCARRH) (DepiSCARRH)

The purpose of this study is to assess the benefit of MR screening for asymptomatic head & neck (or CNS) second primary cancers occurring in hereditary retinoblastoma patients previously

cancer
beam radiation
bilateral retinoblastoma
second primary cancer
  • 28 views
  • 24 Feb, 2022
  • 1 location
PD-1 Inhibitor and Nab-paclitaxel and Bevacizumab in CUP

with albumin paclitaxel and bevacizumab in the second-line treatment of patients with unknown primary tumors.

  • 0 views
  • 30 Apr, 2022
  • 1 location
Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer

acquisition, study participants will take a 7- to 56-day (1-8 weeks) course of letrozole in accordance with standard of care. They will then undergo definitive surgical resection of their primary tumor

letrozole
lumpectomy
raloxifene
breast cancer
renal function
  • 12 views
  • 22 Apr, 2022
  • 1 location
A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases

, increase the possibility of total removal of the primary tumor without local recurrence on longterm follow up. This research study will also determine if pre-operative SRS will lower the risk of

  • 0 views
  • 05 May, 2022
  • 1 location
OMEGA, Local Ablative Therapy in Oligometastatic NSCLC (OMEGA)

tumors has been designed. Inclusion criteria include adequate performance status, primary tumor controlled or controllable staging with whole-body FDG PET scan and brain MRI, fit to receive at

stage iv non-small cell lung cancer
EGFR
metastasis
lung carcinoma
cancer chemotherapy
  • 0 views
  • 24 Feb, 2022
  • 1 location