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Found 6 clinical trials
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

endothelin receptor antagonist
endothelin
stress test
cardiopulmonary exercise testing
diuretics
  • 0 views
  • 24 Nov, 2021
  • 34 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

arginine
pulmonary arterial hypertension
right heart catheterization
endothelin receptor antagonist
angiotensin
  • 6416 views
  • 06 May, 2022
  • 220 locations
Tamoxifen Therapy to Treat Pulmonary Arterial Hypertension (T3PAH)

The main purpose of this clinical trial is to examine the feasibility and effects of tamoxifen in subjects with pulmonary arterial hypertension (PAH). The study will evaluate how well the drug is tolerated, and its impact on functional condition and selected biomarkers. Changes in tricuspid annular plane systolic excursion (TAPSE) …

walk tests
tapse
hypertension
connective tissue disease
  • 82 views
  • 26 Apr, 2022
  • 1 location
Hormonal Metabolic and Signaling Interactions in PAH

Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease.

  • 51 views
  • 04 Jul, 2021
  • 1 location
Pulmonary Hypertension Biorepository and Registry

Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.

right heart catheterization
  • 0 views
  • 10 Jun, 2021
  • 2 locations
Comparison of PD1+T Cell Expression in Peripheral Blood for Cardiac Function Prognosis in Patients With Acute MI

Comparison of high PD1+ T cell and low PD1+ T cell expression in peripheral blood for cardiac function prognosis in Patients with acute myocardial infarction

Accepts healthy volunteers
  • 0 views
  • 13 Mar, 2022
  • 1 location