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Found 6 clinical trials
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Genetic Research of Bone Morphogenetic Protein Receptor-II Gene in Taiwanese Patient With Primary Pulmonary Hypertension

Primary pulmonary hypertension (PPH) is a rare lung disorder in which the blood pressure in the pulmonary artery rises far above normal levels for no apparent reason. The pulmonary artery

pulmonary disease
pulmonary arterial hypertension
primary pulmonary hypertension
  • 0 views
  • 07 Nov, 2020
  • 1 location
None
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

diuretics
cardiopulmonary exercise testing
endothelin receptor antagonist
endothelin
exercise stress test
  • 0 views
  • 24 Oct, 2021
  • 32 locations
None
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

hypertension
beta-blocker
endothelin receptor antagonist
endothelin
arginine
  • 5474 views
  • 18 Oct, 2021
  • 308 locations
None
Tamoxifen Therapy to Treat Pulmonary Arterial Hypertension

The main purpose of this clinical trial is to examine the feasibility and effects of tamoxifen in subjects with pulmonary arterial hypertension (PAH). The study will evaluate how well the drug is tolerated, and its impact on functional condition and selected biomarkers. Changes in tricuspid annular plane systolic excursion (TAPSE) …

walk tests
hypertension
tapse
connective tissue disease
  • 58 views
  • 24 Feb, 2021
  • 1 location
None
Hormonal Metabolic and Signaling Interactions in PAH

Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease.

  • 51 views
  • 04 Jul, 2021
  • 1 location
None
Pulmonary Hypertension Biorepository and Registry

Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.

right heart catheterization
  • 0 views
  • 10 Jun, 2021
  • 2 locations