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Found 62 clinical trials
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A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

intraocular pressure
glaucoma
  • 17 views
  • 10 Mar, 2022
  • 1 location
The Effectiveness of YAG Iridotomy in Preventing Peripheral Anterior Synechia After CLASS in Primary Open Angle Glaucoma

To investigate the effectiveness of YAG laser iridotomy in preventing peripheral anterior synechia after CO2 Laser-Assisted Sclerectomy Surgery and the long-term effect of reducing intraocular pressure

hypotensive
intraocular pressure
brimonidine tartrate ophthalmic solution
primary open angle glaucoma
hypotensive agents
  • 0 views
  • 14 Jun, 2021
  • 1 location
Comparation of CLASS Combined With Phacoemulsification and CLASS Alone in the Treatment of Primary Open Angle Glaucoma

primary open-angle glaucoma

hypotensive
intraocular pressure
primary open angle glaucoma
brimonidine tartrate ophthalmic solution
cataract
  • 0 views
  • 20 Jun, 2021
  • 1 location
The Effect of Dronabinol on Ocular Hemodynamics in Patients With Primary Open Angle Glaucoma

investigate whether single administration of dronabinol alters optic nerve head (ONH) blood flow in patients with open angle glaucoma. In addition, other parameters for ocular blood flow will be measured, in

  • 11 views
  • 12 Sep, 2021
  • 1 location
A Phase III, Multi-center, Randomized, Single-blind (to Evaluator), Parallel, and Positive-controlled Clinical Trial Evaluating the Efficacy and Safety of OPC-1085EL Ophthalmic Solution in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects

primary open angle glaucoma or ocular hypertension in Chinese subjects. It is planned that 240 subjects (120 in each group) will be randomly assigned to receive OPC-1085EL or 0.005% latanoprost ophthalmic

  • 0 views
  • 21 Oct, 2022
  • 1 location
Evaluating Home Testing Devices for the Management of Glaucoma

With the advancement in technology we have the opportunity of performing the glaucoma testing at home to monitor the disease. The purpose of this study is evaluating the feasibility and patient acceptance of home testing with head mounted perimetry; detection of progression with head mounted perimetry vs office based perimetry; …

astigmatism
refractive error
optical coherence tomography
  • 3 views
  • 12 May, 2022
  • 1 location
Adaptive Optics Retinal Imaging

The objective of the study is to collect and assess adaptive optics (AO) retinal images from human subjects in support of projects to demonstrate, advance, and enhance clinical use of AO technology.

Accepts healthy volunteers
  • 0 views
  • 28 May, 2022
  • 1 location
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.

Evaluate the safety and effectiveness of iSTAR Medical's MINIject implant for lowering intraocular pressure (IOP) in subjects with primary open-angle glaucoma.

cataract
filtration surgery
medical therapy
glaucoma surgery
intraocular pressure
  • 0 views
  • 04 Sep, 2021
  • 1 location
A Phase 3b Study to Evaluate the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

This study evaluates the duration of intraocular pressure (IOP)-lowering effect and safety of as needed administrations of Bimatoprost sustained release (SR) in participants with open-angle

intraocular pressure
glaucoma
hypertension
pigmentary glaucoma
brimonidine tartrate ophthalmic solution
  • 426 views
  • 22 Oct, 2022
  • 101 locations
A Phase 3, Randomized, Multi-Regional, Double-Masked, Parallel-Group Trial Evaluating the Safety and Efficacy of NCX 470 0.1% vs. Latanoprost 0.005% in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Denali) (Denali)

-angle glaucoma. Subjects will be randomized in a 1:1 ratio to NCX 470 0.1% or to latanoprost 0.005% to be administered to both eyes once daily in the evening for up to 12 months.

intraocular pressure
hypertension
latanoprost
glaucoma
corrected visual acuity
  • 1 views
  • 11 Oct, 2022
  • 1 location