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Found 42 clinical trials
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Clinical Study of VG161 in Subjects With Advanced Primary Liver Cancer

VG161 is a recombinant human-IL12/15/PDL1B oncolytic HSV-1 Injectable. This phase I study will be conducted in HSV-seropositive subjects with advanced primary liver cancer that are refractory to

  • 0 views
  • 30 Apr, 2021
  • 1 location
None
Efficacy of Intravenous Lidocaine on Postoperative Pain and Recovery in Patients Undergoing Hepatectomy

Patients who meet the enrollment criteria will be randomized 1:1 to either the lidocaine or the placebo group. In the lidocaine group, at the end of the induction of general anesthesia, a bolus injection of lidocaine 1.5 mg/kg, calculated using the patient's ideal body weight and given as an infusion …

  • 0 views
  • 23 Sep, 2021
  • 1 location
None
A Multicenter RCT Study of 3DV Technology in the Diagnosis and Treatment of PLC

Primary liver cancer is the most common malignant tumor of the liver. Radical surgery is the preferred treatment, but its 5-year recurrence rate is as high as 70%, which is often associated with

  • 0 views
  • 20 Nov, 2021
  • 1 location
None
A Non-Randomized Study of Internal Radiation Therapy to the Liver in Patients With Primary Liver Cancer for Whom Surgery is Not Possible.

Surgical resection of the affected liver offers the best chance for disease-free survival in patients with Hepatoma (HCC). Unfortunately, most hepatoma patients present with disease which is multi-focal and thus not resectable. Fewer than 15% of HCC patients are resectable. The objective of treatment with TheraSphere is to selectively administer …

therasphere
hepatoma
serum bilirubin
primary liver cancer
  • 18 views
  • 07 Nov, 2020
  • 1 location
None
Bevacizumab in Advanced Hepatocellular Carcinoma

Primary liver cancer (hepatocellular carcinoma) is the fifth most common malignant disorder, with an increasing incidence in Europe and the USA as a result of the high prevalence of

cancer
chemoembolization
biliary tract cancer
ct scan
cirrhosis
  • 14 views
  • 07 Nov, 2020
  • 1 location
None
Unilateral Versus Bilateral Stents for Bismuth Type II and III Malignant Hilar Strictures

The aim of the present study was to compare the effect of unilateral versus bilateral stenting in patients with malignant hilar obstruction.

biliary stenting
cancer
gallbladder cancer
endoscopic retrograde cholangiopancreatography
biliary obstruction
  • 4 views
  • 07 Nov, 2020
  • 1 location
None
Laparoscope Anatomical and Aon-anatomical Hepatectomy

The purpose of this study is to compare short-term and long-term efficacy of two surgical methods by laparoscopic hepatectomy, and provide the evidence for the choice of surgical method from the pathology and cytology.

radiofrequency ablation
indocyanine green
metastasis
hepatectomy
TACE
  • 4 views
  • 08 Nov, 2020
  • 1 location
None
Durvalumab Plus Tremelimumab Combination Immunotherapy With or Without Weekly Paclitaxel in Patients With Advanced Biliary Tract Carcinoma (BTC) After Failure of Platinum-based Chemotherapy

IMMUNO-BIL is a non-comparative randomized 1:1 phase II study. This study will assess the efficacy and safety of the combination of durvalumab plus tremelimumab with or without weekly paclitaxel in patients with advanced BTC after failure of platinum-based chemotherapy. On the 25th June 2019, the maximum DLT event number was …

  • 2 views
  • 05 Feb, 2021
  • 42 locations
None
Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot be Removed by Surgery

This clinical trial studies radiolabeled glass beads (yttrium Y 90 glass microspheres) in treating patients with unresectable hepatocellular carcinoma. Internal radiation therapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Using radiolabeled glass beads to kill tumor cells may be an effective treatment for …

carcinoma
cancer
hepatocellular carcinoma
liver cancer
unresectable hepatocellular carcinoma
  • 10 views
  • 26 Jan, 2021
  • 1 location
None
  • 0 views
  • 01 Oct, 2021
  • 13 locations