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Found 31 clinical trials
Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery. Giving more chemotherapy after surgery may kill any remaining tumor cells. It is not …

nephroblastoma
tumor cells
cyclophosphamide
conventional surgery
  • 9 views
  • 07 Nov, 2020
  • 1 location
Trial of Active Immunotherapy With Globo H-KLH (OPT-822/821) in Women Who Have Non-Progressive Ovarian Cancer

primary peritoneal cancer after cytoreductive surgery and platinum-based chemotherapy as initial treatment for primary disease or as salvage treatment for first relapse.

fallopian tube
peritoneal cancer
platinum-based chemotherapy
primary peritoneal carcinoma
cytoreductive surgery
  • 36 views
  • 07 Nov, 2020
  • 1 location
Neoadjuvant Therapy Followed by Stereotactic Body Radiotherapy (SBRT) for Locally Advanced Pancreatic Cancer

The purpose of this study is to evaluate a new treatment routine for patients with borderline resectable and unresectable pancreas cancers.

gemcitabine
pancreatic neoplasm
thromboplastin
platelet count
paclitaxel
  • 9 views
  • 08 Nov, 2020
  • 1 location
Phase 3 Trial Evaluating Hyperthermic Intraperitoneal Chemotherapy in Upfront Treatment of Stage IIIC Epithelial Ovarian Cancer

Aim of the Study is to compare two-years disease-free survival of Cytoreductive Surgery (CRS) and Hyperthermic IntraPEritoneal Chemotherapy (HIPEC, CDDP+Paclitaxel) vs CRS alone in Stage IIIC unresectable epithelial tubal/ovarian cancer with partial or complete response after 3 cycles of 1st line chemotherapy (CBDCA +Paclitaxel).

intraperitoneal chemotherapy
cancer of the ovary
ovarian epithelial cancer
ovarian epithelial carcinoma
cytoreductive surgery
  • 67 views
  • 08 Nov, 2020
  • 2 locations
Prospective Trial of Rituximab for Primary Pulmonary Alveolar Proteinosis

The purpose of this study is to determine whether the use of rituximab is effective in treating pulmonary alveolar proteinosis by leading to an improvement in lung function and disease status.

  • 2 views
  • 07 Nov, 2020
  • 1 location
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

This randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small cell lung cancer. Drugs used in maintenance chemotherapy, such as docetaxel, pemetrexed disodium, erlotinib hydrochloride, and gemcitabine work in different ways to stop the growth …

lung cancer
pembrolizumab
systemic chemotherapy
brain metastases
tumor cells
  • 238 views
  • 22 Sep, 2021
  • 194 locations
Routine Health Care of Patients With FSHD

On the basis of published data and our results indicating that oxidative stress may contribute to the peripheral skeletal muscle dysfunction in patients with FSHD, investigators conducted a pilot randomized double-blind placebo controlled trial to test whether oral administration of vitamins and mineral could improve the physical performance of patients …

  • 1 views
  • 25 Jan, 2021
  • 1 location
Culinary Medicine vs. Nutrition Education in Diabetes

This pragmatic trial compares the effectiveness of virtual culinary medicine classes vs. standard of care medical nutrition visits to improve glycemic control in patients with uncontrolled type 2 diabetes . Culinary medicine teaches healthy eating principles through a combination of experiential cooking classes and focused didactic sessions. The primary study …

  • 0 views
  • 23 Sep, 2021
  • 1 location
Study to Evaluate the Efficacy and Safety of Toripalimab in Combination With Axitinib Versus Sunitinib Monotherapy in Advanced Renal Cell Cancer

This is a randomized, open-label, controlled, multicenter, phase III trial to compare the efficacy and safety of Toripalimab in combination with axitinib to sunitinib monotherapy as a first-line therapy for advanced RCC. Eligible patients will be randomized 1:1 to receive the combination therapy of Toripalimab and axitinib or sunitinib monotherapy.

  • 0 views
  • 05 Feb, 2021
  • 1 location
Immunosuppressant Combined With Pirfenidone in CTD-ILD

36 months.The main research endpoints are lung function, patient dyspnea score, 6-minute walking distance, imaging indicators, primary disease activity, adverse reactions, etc.

rheumatism
progressive systemic sclerosis
pirfenidone
dyspnea
immunosuppressive
  • 0 views
  • 24 Jun, 2021
  • 1 location