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Found 3 clinical trials
Role of [18F]-FDG Brain PET in Newly Diagnosed Primary Cerebral Lymphoma in Immunocompetent Patient Older Than 60 Years

Patients older than 60 years account for half of cases of Primary Central Nervous System Lymphoma (PCNSL) and have a poorer outcome. No prognostic or predictive factors exist for survival after initial remission. 18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose - Positron Emission Tomography ([18F]FDG-PET) plays a key role in grading and therapy monitoring of …

hodgkin's lymphoma
primary cerebral lymphoma
bone marrow biopsy
ct scan
  • 25 Jan, 2021
  • 1 location
Maintenance Treatment Versus Observation in Elderly Patients With PCNS Lymphoma

Hypothesis Our hypothesis is that maintenance chemotherapy will prolong complete remission obtained after a standard induction chemotherapy with an acceptable toxicity in the elderly. Rationale Treatment of the elderly is challenging, indeed age over 60 is associated both with a poor prognosis and a high risk of treatment induced neurotoxicity …

maintenance treatment
whole-brain radiotherapy
primary cerebral lymphoma
  • 23 Jan, 2021
Prospective Neurobehavioral Functions in Newly-diagnosed Patients With Primary CNS Lymphoma Treated With Hyperfractionated Conformal Whole-brain Radiation Therapy Plus Simultaneous Integrated Boost

Primary central nervous system lymphoma (PCNSL) is an uncommon disease. Conventional treatment has consisted of either whole-brain radiation therapy (WBRT) or methotrexate (MTX)-based combined modality therapy integrating chemotherapy with cranial irradiation in a sandwiched manner. No matter whether the dosage of MTX is high or conventional, combining chemotherapy with WBRT …

  • 19 Mar, 2021
  • 1 location