Found 427 clinical trials
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Unknown Phase
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Accepting pediatric ages
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Accepting adults
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Oncology
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Currently Recruiting
A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation
A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation
- 164 views
- 24 Nov, 2020
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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Family Medicine
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Currently Recruiting
Food for Thought.
This study is looking for people with mild to moderate Alzheimer’s. The study is testing the effects of eating a study food product.
- 0 views
- 15 Sep, 2020
- 2 locations
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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Currently Recruiting
A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors
A phase II study of Antineoplastons A10 And AS2-1 Private In Children With Primary Malignant Brain Tumors
- 136 views
- 08 Nov, 2020
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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Currently Recruiting
Wake Forest WF-1801 A Single Arm, Pilot Study of Ramipril for Preventing Radiation - Induced Cognitive Decline in Glioblastoma (GBM) Patients Receiving Brain Radiotherapy
People who were just diagnosed with glioblastoma and have yet to get treatment may be eligible. This trial is investigating whether a common blood pressure drug is helpful to prevent or diminish side effects of radiation when it is combined with the standard treatment for glioblastoma.
- 2 views
- 22 Dec, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
OT-15-001 (STELLAR) A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After irradiation and Adjuvant Temozolomide Chemotherapy
People who were previously diagnosed with an anaplastic astrocytoma (WHO grade III astrocytoma) and now have evidence that their tumor has returned or has tarted to grow again without concern that it has progressed to a glioblastoma (WHO grade IV astrocytoma) may be eligible to participate. This study is comparing …
- 10 views
- 22 Dec, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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Oncology
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Currently Recruiting
GBM AGILE An International, Seamless Phase II/III Responsive Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GBM
People with either a new diagnosis of glioblastoma or with evidence that their tumor has returned or started to grow again may be eligible. This trial is studying multiple treatment options, with the results of molecular testing on the tumor determining which arm(s) a person would qualify for. This trial …
- 0 views
- 22 Dec, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Oncology
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Currently Recruiting
CG01-GBM Standard Chemotherapy versus Chemotherapy Chosen by Cancer Stem Cell Chemosensitivity Testing in the Management of Patients with Recurrent Glioblastoma Multiforme (GBM)
People who were previously diagnosed with glioblastoma (Grade IV) or Grade III glioma, and now have evidence that their tumor has come back or has started to grow again, and who would otherwise be getting surgery or a biopsy as part of their treatment may be eligible. At the time …
- 117 views
- 22 Dec, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
N0577 (CODEL) Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q co-deleted Anaplastic Glioma or Low Grade Glioma
People who are diagnosed with an oligodendroglioma and who haven't yet undergone treatment may be eligible. This study is comparing two standard regimens, radiation followed by PCV (Procarbazine, CCNU, and Vincristine) or radiation with temozolomide during and after radiation, to see which is better.
- 10 views
- 22 Dec, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
Alliance A071701 Genomically-Guided Treatment Trial in Brain Metastases
People with recurrent or progressive brain metastases may be eligible for this trial. All tumors will be submitted to the Alliance biorepository for tracking and processing. Samples will undergo central biomarker testing. Patient's tumor samples will be tested for the presence of mutations predicting sensitivity to each inhibitor. Patients harboring …
- 40 views
- 22 Dec, 2020
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Study on Tailored Treatment in Elderly Patients With Newly Diagnosed Primary Lymphoma of Central Nervous System
Primary central nervous system lymphomas are rare aggressive malignancies, usually treated in two steps: an induction phase (where a combination of chemotherapy is given) followed by a consolidation phase (where patients usually receive one of the following: whole-brain irradiation, chemotherapy supported by autologous stem-cell transplantation, other type of chemotherapy, or …
- 0 views
- 15 Oct, 2020
- 38 locations