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Found 74 clinical trials
Comparison of the Nociception Monitoring Devices During Cardiac Surgery.

The purpose of this study is to compare the values of Surgical Pleth Index (SPI) and Nociception Level Index (NOL) measured simultaneously during cardiac surgery.

  • 23 Sep, 2021
  • 1 location
Assessment of Cardiac Coherence Associated With Medical Hypnosis on Preoperative Anxiety in Oncological Surgery (COHEC2)

The investigator proposes to use the cardiac coherence technique (Cardiac Coherence) coupled with a hypnosis session to reduce pre-operative anxiety.

  • 27 May, 2022
  • 1 location
The Effect of Reading Story Books on Fear and Anxiety Levels

The aim of this project is to determine the effect of reading the story book, which is considered within the scope of the pedagogically approved research that introduces the surgical environment before the surgical intervention in children, on the pain and anxiety of the child. The project is a randomized …

  • 11 Aug, 2022
  • 1 location
Efficacy and Safety of Activated T Lymphocytes (ATL) in Hepatocellular Carcinoma

This is an open-label, single arm, multicenter, Phase II clinical study to investigate the efficacy and safety profiles of autologous ATL administration in HCC patients after curative treatment. Among all the eligible patients, ratio of 7:2:1 for Stage I:II:IIIa of the HCC will be the enrolled strategy of the study …

  • 03 Jul, 2022
  • 1 location
The Effect of Intraoperative Music Listening on Sevoflurane Consumption and Recovery Parameters

The perioperative period can be a significant source of psychological burden, anxiety and fear for patients Both pharmacological and non-pharmacological methods have been proposed in order to alleviate perioperative stress Music is one of the non-pharmacological methods which have been used in this context, with favorable effects both preoperatively and …

  • 21 Mar, 2022
  • 1 location
Lateral Versus Posterior Quadratus Lumborum Block in The Pediatric Patients Undergoing Orchiopexy

There is a complex innervation of the testis and spermatic canal, and many different regional analgesia methods can be used for pain occurring during and after undescended testicular surgery. Quadratus lumborum block (QLB) can be count as the one of the primary method to manage the pain. In this study, …

pain relieving
postoperative pain
  • 06 Oct, 2021
  • 1 location
A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001) (GRASP)

A promising approach for the treatment of genetic diseases is called gene therapy. Gene therapy is a relatively new field of medicine in which genetic material (mostly DNA) in the patient is changed to treat his or her own disease. In gene therapy, we introduce new genetic material in order …

bone marrow transplant
conjugated bilirubin
sickle hemoglobin
vaso-occlusive crisis
  • 23 Jul, 2022
  • 1 location
The Effect of Preoperative Active Warming on Intraoperative Body Temperature

A randomized controlled study was conducted to examine the effect of active warming before total knee arthroplasty on intraoperative body temperature and comfort.

  • 06 May, 2022
  • 1 location
Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease (LIVERPEARL)

Non-commercial, prospective, randomized, multicenter, national, phase II, open-label comparative clinical trial. The patients will be randomized in a 1: 1 ratio in two arms: Control arm. Systemic chemotherapy with FOLFOX6m + monoclonal Ab Experimental arm. Systemic chemotherapy with FOLFOX6m + monoclonal Ab + Intra-arterial liver chemotherapy with LIFEPEARLS-IRINOTECAN (catheterization and …

  • 23 Mar, 2022
  • 7 locations
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients (TRASTS)

Phase I-II trial that combines trabectedin plus radiotherapy for tumor reduction response measure in two cohorts of patients: Cohort A: Patients with diagnosis of non-operable or unresectable or not oncologically recommended metastasectomy of limited to lung metastases soft tissue sarcoma. Cohort B: Patients with locally advanced resectable Myxoid Liposarcoma. Cohort …

synovial sarcoma
cancer chemotherapy
soft tissue sarcoma
  • 17 Jun, 2022
  • 13 locations