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Found 67 clinical trials
Respiratory Effect of the LISA Method With Sedation by Propofol Versus Absence of Sedation. (PROLISA)

The investigators propose to evaluate premedication with Propofol compared to a control strategy including a placebo with a possible rescue treatment with ketamine to ensure pain control before

  • 18 Feb, 2022
  • 16 locations
A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease

This study aims to define the efficacy and safety of inebilizumab for the prevention of flare of IgG4-related disease (IgG4-RD).

  • 23 Apr, 2022
  • 71 locations
Premedication by Clonidine Intranasal in Pediatric Surgery

There are few studies using intra nasal way to dispense premedication in pediatrics. This study will evaluate anxiolysis effect of Intranasal premedication with Clonidine vs Placebo.

  • 19 Mar, 2021
  • 1 location
Mirtazapine Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting

nausea and vomiting has been reported in the literature, both for treatment and premedication. Dexamethasone, possesses analgesic, anti-inflammatory, immune-modulating, and antiemetic effects

Accepts healthy volunteers
  • 10 Aug, 2022
  • 1 location
The PREVENT AGITATION Trial II - Children 1 Year

. sedation in the intensive care unit, prevention of withdrawal symptoms after long-term sedation, as premedication before induction of anaesthesia or as treatment/prevention of emergence agitation. The

  • 20 Nov, 2021
  • 1 location
Open-label Dose Escalation Phase 1b Trial of a New Micellar Docetaxel Compound in Patients With mCRPC

well known immunosuppressive effects. Despite steroid premedication, polysorbate 80-solved Docetaxel (Taxotere®) results in occasional infusion reactions due to the solvent polysorbate 80. Docetaxel

  • 07 Jan, 2022
  • 3 locations
Evaluation of the Interest of a Virtual Reality Headset on Pain and Anxiety During Epidural Injection Through the Sacrococcygeal Hiatus in Patients With Lumbar Radicular Pain. (Epi-RéV)

this procedure is performed without premedication. To the knowledge of the investigators, there are currently no studies on the assessment of pain under a virtual reality headset during the

  • 20 Sep, 2022
  • 1 location
Antithymocyte Globulin as a Second Line Therapy in Graves Orbitopathy

The overall objective of the study is to evaluate the safety and efficacy of rabbit antithymocyte globulin in the treatment of Graves orbitopathy (GO) after ineffective treatment with moderate-to-high doses of glucocorticoids.

  • 25 Mar, 2022
Comparison Between the Analgesic Effects of Ultrasound-guided Unilateral Quadratus Lumborum Block (Lateral Approach) Versus Erector Spinae Plane Block in Patients Undergoing Unilateral Lower Abdominal Surgery

The wall of abdomen is a considerable source of discomfort and pain following abdominal surgery even after a somewhat small operation like inguinal herniorrhaphy which could be source of chronic pain in 12% of patients, with considerable clinically effect on daily behavior if post operative pain is not considered in …

  • 22 Sep, 2022
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane

The purpose of this protocol is to determine the effect of two clinically applicable Dexmedetomidine dosages (0.5mcg/kg and 1mcg/kg) on the minimum alveolar concentration (MAC) of Sevoflurane in children between the age ranges of: 1-6 months; 6-12 months of age and 12 months-36 months years of age.

Accepts healthy volunteers
  • 27 Apr, 2022
  • 1 location