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Found 49 clinical trials
Respiratory Effect of the LISA Method With Sedation by Propofol Versus Absence of Sedation. (PROLISA)

The investigators propose to evaluate premedication with Propofol compared to a control strategy including a placebo with a possible rescue treatment with ketamine to ensure pain control before

  • 18 Feb, 2022
  • 16 locations
A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease

This study aims to define the efficacy and safety of inebilizumab for the prevention of flare of IgG4-related disease (IgG4-RD).

  • 23 Apr, 2022
  • 71 locations
Premedication by Clonidine Intranasal in Pediatric Surgery

There are few studies using intra nasal way to dispense premedication in pediatrics. This study will evaluate anxiolysis effect of Intranasal premedication with Clonidine vs Placebo.

  • 04 Oct, 2022
  • 1 location
The PREVENT AGITATION Trial II - Children 1 Year

. sedation in the intensive care unit, prevention of withdrawal symptoms after long-term sedation, as premedication before induction of anaesthesia or as treatment/prevention of emergence agitation. The

  • 20 Nov, 2021
  • 1 location
Open-label Dose Escalation Phase 1b Trial of a New Micellar Docetaxel Compound in Patients With mCRPC

well known immunosuppressive effects. Despite steroid premedication, polysorbate 80-solved Docetaxel (Taxotere®) results in occasional infusion reactions due to the solvent polysorbate 80. Docetaxel

  • 07 Jan, 2022
  • 3 locations
Interest of Virtual Reality Headset During Injection in Patients With Back Pain and Sciatica (Epi-RéV)

this procedure is performed without premedication. To the knowledge of the investigators, there are currently no studies on the assessment of pain under a virtual reality headset during the

  • 07 Oct, 2022
  • 1 location
Antithymocyte Globulin as a Second Line Therapy in Graves Orbitopathy

The overall objective of the study is to evaluate the safety and efficacy of rabbit antithymocyte globulin in the treatment of Graves orbitopathy (GO) after ineffective treatment with moderate-to-high doses of glucocorticoids.

  • 25 Mar, 2022
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane

The purpose of this protocol is to determine the effect of two clinically applicable Dexmedetomidine dosages (0.5mcg/kg and 1mcg/kg) on the minimum alveolar concentration (MAC) of Sevoflurane in children between the age ranges of: 1-6 months; 6-12 months of age and 12 months-36 months years of age.

Accepts healthy volunteers
  • 27 Apr, 2022
  • 1 location
Lung UltrasouNd Guided Surfactant Therapy in Preterm Infants (LUNG Study) (LUNG)

The investigators hypothesized that the use of lung ultrasound (LU) for measuring RDS severity and deciding surfactant treatment thresholds might decrease the incidence of early and late sequelae in the study group. Thus, a timely surfactant therapy would eventually improve short (e.g. Need of mechanical ventilation in the first 3 …

  • 04 Oct, 2022
  • 12 locations
Anesthetic Premedication With a Cannabis Extract (Cannapremed) (Cannapremed)

Clinical evidence about the effects of cannabis in a perioperative setting or for the management of acute pain is rather scarce, mostly consisting of case report-based opinions on adverse events during or after general anesthesia after smoking cannabis, experimental pain trials in healthy volunteers, and a few clinical trials using …

acute pain
respiratory depression
  • 11 Apr, 2022
  • 1 location