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Found 11 clinical trials
LLTS to Treat Premature Ventricular Contractions

This randomized control trial is designed to explore the effect of low-level tragus stimulation in patients with frequent premature ventricular contractions.

  • 30 Jun, 2021
  • 1 location
Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.

Accepts healthy volunteers
  • 25 Feb, 2022
  • 1 location
Non-invasive Vagal Stimulation for Frequent Premature Ventricular Complexes (NoVa-PVC) ((NoVa-PVC))

A prospective sham-controlled randomized clinical trial to assess the effect of low-level tragus stimulation (LLTS) in patients with frequent premature ventricular complexes (PVCs)

  • 23 Sep, 2022
  • 1 location
  • 18 Sep, 2022
  • 18 locations
Clinical Evaluation of Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter (COSMOS)

The purpose of this study is to assess the performance and safety for the use of the investigational catheter for intracardiac mapping in the atria and ventricles.

  • 19 Sep, 2022
enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening (enHEART)

This research will investigate the PPG signal morphology related to physiological and nonphysiological changes in arrhythmia-related heart rate as well as the performance of the PPG-based features previously developed within the framework of the Mini-Holter study to discriminate between several cardiac arrhythmias. To this end, clinical data will be recorded …

atrial flutter
ventricular tachycardia
12 lead ECG
ventricular extrasystoles
  • 06 Apr, 2022
  • 1 location
Impact of Pacing Output and Cycle Length on QRS Morphology

Current recommendations for pacemapping are based on expert opinion and animals models. Present study sought to evaluate the influence of different parameters of pacemapping on QRS morphology. Pacemapping is performed with different cycle length (fixed burst vs. coupling interval) and stimulation output (maximum output vs. threshold) and resulting QRS complexes …

  • 16 Nov, 2021
  • 1 location
PASO Automated Template Matching for PVC Ablation

Pacemapping is an essential tool during ablation of idiopathic PVC and VT. Automated template matching has been shown to have a significant influence on PVC ablation procedures, but the PASO module of CARTO3 has not been studied in a randomized trial. The Aim of this study is to evaluate the …

  • 15 Mar, 2021
  • 1 location
Prevention of Stroke and Sudden Cardiac Death by Recording of 1-Channel Electrocardiograms (PRICE)

Single-channel electrocardiograms (lead I of 12-lead surface ECG; 30 seconds) will be collected from subjects/patients at 11 clinical centers in Germany to train an Artificial Intelligence in the automatic diagnosis of regular and irregular heart rhythms. Heart rhythms of interest are normal sinus rhythm (SR), atrial fibrillation (AF), atrial premature …

ventricular tachycardia
diagnostic procedure
cardiac death
  • 18 Apr, 2022
Personalized Treatment for Patients With Premature Ventricular Beats

Frequent premature ventricular beats (PVBs) are common, negatively affects the quality of life for many patients, and can lead to impaired contractile function. Rule-out of structural heart disease is key in the assessment of PVBs. Cardiac MR has a high sensitivity for structural heart disease, but the diagnostic gain from …

  • 29 Apr, 2022
  • 1 location