Found 296 clinical trials
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Unknown Phase
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Accepting Seniors
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Accepting adults
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Family Medicine
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Currently Recruiting
A Study of the Kinetics of Lymphoid Cells in Patients with Monoclonal B-Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL) and Healthy Volunteers
have not been taking certain agents (Viagra, Levitra, Cialis, or other PDE-inhibitors, prednisone, cyclosporin-A, rapamycin, or other immunosuppressive agents, more than 2 cups of green tea daily, or
- 102 views
- 15 Apr, 2019
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Accepting Seniors
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Family Medicine
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Currently Recruiting
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy
, mycophenolate mofetil and prednisone to prevent rejection of the donated cells and to prevent graft-versus-host disease (GVHD), a complication of stem cell transplants in which the donor s immune cells destroy
- 48 views
- 22 Dec, 2020
- 1 location
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase IV Study to Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and COPD Exacerbations in Patients with Moderate to Very Severe COPD
Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase IV Study to Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and COPD Exacerbations in Patients with Moderate to Very Severe COPD
- 156 views
- 23 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Currently Recruiting
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)
- 674 views
- 08 Nov, 2020
- 1 location
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Phase 4 trial
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Accepting pediatric ages
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Accepting adults
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Currently Recruiting
Do You Have Osteoporosis?
Do You Have Osteoporosis?
- 1122 views
- 08 Nov, 2020
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Currently Recruiting
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
The purpose of the study is to determine if the combination of niraparib with Abiraterone Acetate (AA) plus prednisone compared with AA plus prednisone in participants with deleterious germline
- 0 views
- 19 Dec, 2020
- 364 locations
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Multi-country trial
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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1000s of participants
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An interventional trial
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For males only
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Currently Recruiting
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
be nine cohorts in this study: Cohort A will receive pembrolizumab + olaparib, Cohort B will receive pembrolizumab + docetaxel + prednisone, Cohort C will receive pembrolizumab + enzalutamide, Cohort
- 0 views
- 12 Dec, 2020
- 11 locations
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Multi-country trial
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Currently Recruiting
Investigation of Radium-223 Dichloride (Xofigo) a Treatment That Gives Off Radiation That Helps Kill Cancer Cells Compared to a Treatment That Inactivates Hormones (New Antihormonal Therapy NAH) in Patients With Prostate Cancer That Has Spread to the Bone Getting Worse on or After Earlier NAH
study will be either abiraterone acetate (Zytiga) (plus prednisone/prednisolone) or enzalutamide (Xtandi). Both of them are standard approved medications which are used in the treatment of advanced
- 0 views
- 01 Jan, 2021
- 140 locations
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An interventional trial
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For all genders
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Ophthalmology
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Currently Recruiting
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial
Non-infectious intermediate, posterior, and panuveitides are chronic, potentially-blinding diseases. Vision-threatening cases require long-term therapy with oral corticosteroids and immunosuppression. Based upon preliminary data, adalimumab, a fully-human, anti-TNFmonoclonal antibody, now US FDA-approved for uveitis treatment, may be a superior corticosteroid-sparing agent than conventional immunosuppressive drugs. The ADVISE Trial is multicenter randomized, …
- 103 views
- 13 Aug, 2020
- 27 locations
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Multi-country trial
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Phase 1 trial
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Accepting pediatric ages
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Accepting Seniors
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Gene Transfer Clinical Trial for Mucopolysaccharidosis (MPS) IIIB
Open-label, dose-escalation clinical trial of rAAV9.CMV.hNAGLU injected intravenously through a peripheral limb vein
- 6 views
- 23 Sep, 2020
- 4 locations