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Found 140 clinical trials
Individualized Targeting and Neuromodulation of Late-Life Depression (TMS-LLD)

An open-label, single-arm, clinical research study about how to make transcranial magnetic stimulation (TMS), an FDA-approved treatment, more effective for patients with late-life depression using fMRI.

  • 22 Aug, 2023
  • 1 location
Biomarkers of ADHD Treatment Response (BAT)

The goal of this translational biomarker study is to use electroencephalography (EEG) to identify brain signatures that will predict a child's response to two of the most commonly prescribed ADHD medications, methylphenidate and mixed amphetamine salts. The main questions the investigators aim to answer are: Do children with ADHD who …

  • 09 Sep, 2023
Exercise in Child Health (Project REACH)

This study is a cooperative investigation funded by the NIH. The project is a collaboration among three major NIH Clinical Translational Science Awardees: 1) UCI (lead site with its affiliate CHOC), 2) Northwestern University (with its affiliate Lurie Children's Hospital), and 3) USC (with its affiliate Children's Hospital of Los …

Accepts healthy volunteers
cardiopulmonary exercise testing
  • 15 May, 2022
  • 1 location
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy (ROME)

This is a randomized, prospective, multicenter, Proof of Concept, Phase II clinical trial Study. The main objective of the study is to evaluate the efficacy (meant as overall response rate ORR) of TT (targeted Therapy) vs SoC (standard of Care) in patients with progressive disease (recurrent and/or metastatic) of breast …

kidney function test
  • 17 May, 2022
  • 38 locations
Functional Interval Training for Veterans Exercising Through Telehealth. (FIT-VET)

Most Veterans living with HIV are 50 years of age or older and can expect to live more than 20 years longer with HIV medication. However, despite this success, Veterans living with HIV are more likely to have age-related diseases and loss of fitness and muscle that place them at …

antiretroviral therapy
  • 22 Mar, 2022
  • 3 locations
Functional and Cognitive Rehabilitation of Hoarding Disorder (CREST)

Hoarding Disorder (HD) is serious and disabling in Veterans. Present in up to 7% of Veterans and even higher symptom rates in older Veterans; HD contributes to functional impairment and poor quality of life. Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) has shown promising functional improvement and symptom reduction. To reduce …

exposure therapy
  • 04 Oct, 2022
  • 1 location
Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum

The investigators will conduct a randomized controlled clinical trial study in an urban emergency department in Baltimore to determine the impact of an educational app which is based on Leventhal's Common-Sense Model of Illness Representations framework, on HCV-infected ED patient's hepatitis C virus (HCV) health belief and knowledge as well …

  • 11 Apr, 2023
  • 1 location
Trial of Preemptive Pharmacogenetics in Underserved Patients (ToPP-UP)

This proposed research is relevant to human health because preemptive clinical pharmacogenetic testing may improve the personalization of drug therapy which should improve patient outcomes. Better understanding of the effectiveness and feasibility of preemptive clinical pharmacogenetic testing will inform when and how this innovative healthcare technology is implemented into clinical …

  • 18 Sep, 2023
  • 1 location
Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

Background Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma. Most people with this cancer can be cured. But those who are not cured have a poor prognosis. Researchers want to add another drug to standard treatment see if it can improve the cure rate. Objective To …

diffuse large b-cell lymphoma
hodgkin's disease
granulocyte colony stimulating factor
  • 18 Sep, 2023
  • 1 location
SHOWME-PAD (Peripheral Artery Disease)

The overall goal of SHOWME-PAD is to make the existing evidence-base on treatment outcomes -focusing on health status outcomes that reflect the patients' perspective - more transparently available to patients and providers, such that more informed, evidence-based shared treatment decisions occur. INTEGRITY-PAD has the potential to radically reorganize care delivery …

peripheral arterial diseases
  • 21 Apr, 2022
  • 1 location